Antiphospholipid syndrome is the one autoimmune noninflammatory syndrome affecting all blood vessels at any vascular segment, irrespective of the vascular size and topography. Defined in 1983 by Hughes, this syndrome represents the actual research theme in practically all medical fields, therefore the importance of antiphospholipid syndrome is recognized. The major aim of this article is to describe the neuro-ophthalmologic manifestations of the antiphospholipid syndrome, emphasizing the latest news about this syndrome and its impact on the retina and central nervous system.
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