Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/00015550410025895 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Juvenile pemphigus vulgaris: Literature review and a rare case report.
Clin Case Rep
May 2024
Department of Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences Saveetha University Chennai India.
Pemphigus vulgaris (PV) is a chronic autoimmune blistering disorder characterized by the loss of intraepithelial adhesion affecting the skin and mucous membranes, predominantly affects females in their fifth and sixth decades of life. Due to its rare occurrence in children and adolescents, there is often a delay in diagnosis and treatment in this age group. PV should always be considered in the differential diagnosis of oral ulcerative and vesiculobullous lesions in both children and adolescents.
View Article and Find Full Text PDFRituximab in Childhood and Juvenile Pemphigus Vulgaris: A Systematic Review.
Cureus
April 2024
Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, IND.
Article Synopsis
- - Pemphigus vulgaris (PV) is a rare autoimmune skin disorder that can affect both genders but is more common in females in their 50s and 60s; about 1.4 to 3.7% of cases occur in children and adolescents, leading to delayed diagnosis.
- - A systematic review was conducted on various studies to assess the effectiveness of rituximab (RTX) in treating childhood and juvenile PV, with 18 studies involving 46 patients analyzed for treatment outcomes.
- - Most pediatric patients treated with RTX achieved remission, experienced few relapses, and had only minor side effects; however, the limited evidence and lack of controlled studies call for more research to create a standardized treatment approach.
Clinical course and therapeutic management of juvenile pemphigus vulgaris: A retrospective analysis from an Italian referral centre.
J Eur Acad Dermatol Venereol
June 2024
Dermatology Unit, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Pemphigus foliaceus is an autoimmune blistering disease of the skin that is not frequently associated with mucous membrane involvement. It is characterized by immunoglobulin G (IgG) antibodies against desmoglein-1, a component of epidermal intercellular adhesion, in the granular layer of the epidermis. Pemphigus foliaceus consists of scattered, arcuate, crusted erythematous lesions often in a seborrheic distribution that may progress to diffuse skin involvement and exfoliative erythroderma.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!