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Rapid reversal of renal failure after initiation of HAART: a case report. | LitMetric

Rapid reversal of renal failure after initiation of HAART: a case report.

AIDS Read

Department of Internal Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.

Published: August 2004

AI Article Synopsis

  • HIV-associated nephropathy (HIVAN) leads to proteinuria and renal failure in HIV patients, and treatment options include corticosteroids, ACE inhibitors, and HAART.
  • While some case reports suggest HAART can improve renal function, there hasn't been a systematic study on its effectiveness or timing.
  • This text presents a specific case where a patient with biopsy-confirmed HIVAN experienced rapid recovery from end-stage renal failure after starting HAART.

Article Abstract

HIV-associated nephropathy (HIVAN), characterized by proteinuria and progressive renal failure, is a well-known complication of HIV infection. Treatment of the condition has focused on the use of corticosteroids, angiotensin-converting enzyme inhibitors, and HAART, all of which can improve the prognosis. Although there are a few case reports of improvement of renal function after the initiation of HAART, this treatment has not been studied in a prospective fashion, and the timing of the improvement is not well documented. Presented here is a case of rapid reversal of end-stage renal failure after the initiation of HAART in a person with biopsy-proven HIVAN.

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