The biopharmaceutical industry is currently being presented with opportunities to improve research and business efficiency via automation and the integration of various systems. In the examples discussed, industrial high-throughput screening systems are integrated with functional tools and bioinformatics to facilitate target and biomarker identification and validation. These integrative functional approaches generate value-added opportunities by leveraging available automation and information technologies into new applications that are broadly applicable to different types of projects, and by improving the overall research and development and business efficiency via the integration of various systems.
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http://dx.doi.org/10.1517/14622416.5.6.721 | DOI Listing |
PLoS One
January 2025
Department of Operations Analytics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Integrating Supply Chain Optimization (SCO) with Life Cycle Assessment (LCA) is essential for creating supply chains that are both economically efficient and environmentally sustainable. While SCO focuses on optimizing network structures and decisions related to product and service delivery, LCA systematically assesses the environmental impacts across the entire supply chain. The existing literature treats SCO and LCA as separate, sequential steps, often leading to inconsistencies in scope and challenges in data transfer and rescaling.
View Article and Find Full Text PDFJ Neurol
January 2025
Department of Sustainable Health, University of Groningen, Campus Fryslân, Wirdumerdijk 34, 8911 CE, Leeuwarden, The Netherlands.
Background: Neurological disorders pose a substantial burden worldwide in healthcare and health research. eHealth has emerged as a promising field given its potential to aid research, with lower resources. With a changing eHealth landscape, identifying available tools is instrumental for informing future research.
View Article and Find Full Text PDFRes Pract Thromb Haemost
January 2025
Department of Clinical Chemistry, MaasstadLab, Maasstad Hospital, Rotterdam, the Netherlands.
Background: Pulmonary embolism (PE) is a life-threatening condition with high morbidity and mortality. The diagnosis of PE is challenging due to nonspecific symptoms, making reliable diagnostic tools essential. This study addresses the clinical impact of interassay variability in D-dimer measurements on the utilization and diagnostic yield of computed tomography pulmonary angiography (CTPA).
View Article and Find Full Text PDFBJPsych Bull
January 2025
University of Warwick, Coventry, UK.
Modern management has much to learn from ancient wisdoms. Management structures based on corporate trends were transferred from business to services such as healthcare to promote cost-efficiency and productivity. In this article, I argue that the short-term approach of corporate leaders being brought into healthcare for 'transformation' has led to a trail of service dismemberment with no discernible clinical gain for those we seek to serve.
View Article and Find Full Text PDFBMC Genomics
January 2025
College of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Background: Identifying markers or genes crucial for growth traits in Zhongwei goats is pivotal for breeding. Pinpointing genetic factors linked to body size gain enhances breeding efficiency and economic value. In this study, we used the MGISEQ-T7 platform to re-sequence 240 Zhongwei goats (133 male; 107 female) belonging to 5 metrics of growth traits at different growth stages (40 days and 6 months, here in after referred to as 40d and 6 m), namely, Body Weight (BW), Body Height (BH), Body Length (BL), Chest Circumference (CC), Tube Circumference (TC) were examined.
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