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http://dx.doi.org/10.1126/science.305.5688.1239 | DOI Listing |
J Endocrinol Invest
December 2024
Clinic for Radiology, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland.
Objectives: Ultrasound (US) evaluation is recognized as pivotal in assessing the risk of malignancy (RoM) of thyroid nodules (TNs). Recently, various US-based risk-classification systems (Thyroid Imaging and Reporting Data Systems [TIRADSs] have been developed. An important ongoing project concerns the creation of an international system (I-TIRADS) using unique terminology.
View Article and Find Full Text PDFSci Data
October 2024
Sydney Musculoskeletal Health and The Kolling Institute, Northern Clinical School, Faculty of Medicine and Health and the Northern Sydney Local Health District, Sydney, NSW, Australia.
Radiographic landmark annotation determines patients' anatomical parameters and influences diagnoses. However, challenges arise from ambiguous region-based definitions, human error, and image quality variations, potentially compromising patient care. Additionally, AI landmark localization often presents its predictions in a probability-based heatmap format, which lacks a corresponding clinical standard for accuracy validation.
View Article and Find Full Text PDFMol Diagn Ther
January 2025
OncoAtlas LLC, Leninsky Ave, 1/4A, Moscow, 119049, Russia.
Background: The widespread use of next-generation sequencing in clinical practice has contributed to the accumulation of a large number of genomic findings associated with targeted therapy; therefore, the problem of ranking the detected findings has become acute. The European Society for Medical Oncology Scale of Clinical Actionability of molecular Targets (ESCAT) system was designed by the European Society for Medical Oncology to rank biomarkers into levels of evidence that reflect their potency and clinical significance based on published clinical data. However, the ESCAT system remains imperfect, as it is based on a subjective assessment of the levels of evidence.
View Article and Find Full Text PDFPhys Chem Chem Phys
August 2024
Univ Rennes, CNRS, IPR (Institut de Physique de Rennes), UMR 6251, F-35000 Rennes, France.
CH was the first molecular ion identified in the interstellar medium and is found to be ubiquitous in interstellar clouds. However, its formation and destruction paths are not well understood, especially at low temperatures. A new theoretical approach based on the canonical variational transition state theory was used to study the H + CH reactive collisions.
View Article and Find Full Text PDFClin Teach
December 2024
Medical School, Padre Albino University Center (FAMECA-UNIFIPA), Catanduva, São Paulo, Brazil.
Background: Human cadavers are an important component of anatomy education; however, they have limitations. In this scenario, alternative artificial models emerge to complement teaching and enable learning in environments with scarce resources. The following study aims to demonstrate the elaboration of handmade cold porcelain models and their acceptance by medical students in a Brazilian university.
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