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Possible linking and treatment between Parkinson's disease and inflammatory bowel disease: a study of Mendelian randomization based on gut-brain axis.
J Transl Med
January 2025
Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.
Background: Mounting evidence suggests that Parkinson's disease (PD) and inflammatory bowel disease (IBD) are closely associated and becoming global health burdens. However, the causal relationships and common pathogeneses between them are uncertain. Furthermore, they are uncurable.
View Article and Find Full Text PDFMonitoring of Selected Swine Viral Diseases in Peruvian Amazon Peccaries.
Ecohealth
January 2025
Wildlife Conservation Medicine Research Group (WildCoM), Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Peccaries (collared peccary-CP-and white-lipped peccary-WLP) are an essential source of protein and income for rural communities in the Amazon region. Since 1980s, researchers in the Amazon have reported recurrent local disappearances of WLP populations. Although such disappearances impact the species conservation and the food security of rural societies, no studies have drawn consistent conclusions about the causes of these population collapses.
View Article and Find Full Text PDFGenetic variations in IGF2BP2 and CAPN10 and their interaction with environmental factors increase gestational diabetes mellitus risk in Chinese women.
Gene
January 2025
Department of Immunology, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China. Electronic address:
Aim: This study aims to investigate the association of the genetic variations in IGF2BP2 and CAPN10 as well as gene-environment interactions with the risk of gestational diabetes (GDM) in Chinese women.
Materials And Methods: A total of 1,566 pregnant Chinese women participated in this case-control study. We employed targeted next-generation sequencing to analyze specific SNPs in IGF2BP2 (rs11927381, rs1470579, rs4402960, rs7640539) and CAPN10/rs2975760.
Ancestral carbonic anhydrase with significantly enhanced stability and activity for CO capture and utilization.
Bioresour Technol
January 2025
Department of Bioengineering and Biotechnology, Huaqiao University, Xiamen 361021, Fujian Province, PR China. Electronic address:
Carbonic anhydrases (CAs) has garnered increasing attention in carbon capture, utilization and storage (CCUS) due to their ecological friendliness. However, most of them suffer susceptibility to deactivation in harsh conditions. Herein, a reliable dataset was adopted for creating ancestral CAs through an optimized ancestral sequence reconstruction (ASR) method.
View Article and Find Full Text PDFDynamically mechanochromic, fluorescence-responsive, and underwater sensing cellulose nanocrystal-based conductive elastomers.
Int J Biol Macromol
January 2025
Jiangsu Co-Innovation Center for Efficient Processing and Utilization of Forest Resources, Jiangsu Provincial Key Lab Pulp & Paper Science and Technology, Nanjing Forestry University, Nanjing 210037, PR China. Electronic address:
Utilizing cellulose nanocrystals (CNCs) to mimic biological skin capable of converting external stimuli into optical and electrical signals represents a significant advancement in the development of advanced photonic materials. However, traditional CNC photonic materials typically exhibit static and singular optical properties, with their structural color and mechanical performance being susceptible to water molecules, thereby limiting their practical applications. In this study, CNC-based conductive elastomers with dynamic mechanochromism, fluorescence responsiveness, and enhanced water resistance were developed by incorporating carbon quantum dots (C QDs) and hydrophobic deep eutectic solvents (HDES) into CNC photonic films via an in-situ swelling-photopolymerization method.
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