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Self-driven micromotors loaded with photosensitive adhesives and their application in dentin sensitivity.
J Mater Chem B
January 2025
Oral Implant Centre, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, People's Republic of China.
Dentin hypersensitivity is primarily caused by the exposure of dentinal tubules due to various factors, so the key to treatment is to effectively seal these exposed tubules. However, traditional dentinal tubule sealants used in clinical practice often fail to adhere securely to the tubule surface when exposed to external stimuli, resulting in a recurrence of sensitivity. In this study, we developed a silicon micromotor that moved autonomously and loaded with silver nanoparticles and a photosensitive adhesive for dentin sensitivity therapy.
View Article and Find Full Text PDFBioadhesives and bioactive hydrogels for wound management.
J Control Release
January 2025
Department of Bioengineering and Nano-Bioengineering, College of Life Sciences and Bioengineering, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, Republic of Korea; Research Center for Bio Materials & Process Development, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, Republic of Korea. Electronic address:
Delayed wound healing remains a major challenge in biomedical research, often leading to complications such as scarring, acute trauma, and chronic diseases. Effective wound management is crucial for enhancing treatment outcomes, preventing complications, and promoting tissue regeneration. In response to this need, a variety of polymeric biomaterials have been developed.
View Article and Find Full Text PDFA nanochitin-drived natural biological adhesive with high cohesive for wound healing.
Int J Biol Macromol
January 2025
Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering, Nanjing Forestry University, Longpan Road 159, Nanjing 210037, China. Electronic address:
The weak cohesive strength of tissue adhesives hinders their practical applications. To overcome this challenge, we develop a green bio-adhesive that balances both cohesion and adhesion, drawing inspiration from the natural adhesion mechanisms of mussels. This bio-adhesive, referred to as OTS, was ingeniously crafted through the co-assembly of multi-surface-charged chitin nanofibers (OAChN) and tannic acid (TA), integrated with silk fibroin (SF), resulting in a material with enhanced cohesive strength and robust adhesive properties.
View Article and Find Full Text PDFDynamic Peptide Nanoframework-Guided Protein Coassembly: Advancing Adhesion Performance with Hierarchical Structures.
J Am Chem Soc
January 2025
Engineering Research Center of Advanced Rare Earth Materials (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
Hierarchical structures are essential in natural adhesion systems. Replicating these in synthetic adhesives is challenging due to intricate molecular mechanisms and multiscale processes. Here, we report three phosphorylated peptides featuring a hydrophobic self-assembly motif linked to a hydrophilic phosphorylated sequence (pSGSS), forming peptide fibril nanoframeworks.
View Article and Find Full Text PDFAortic lumen repair with glue-felt technique before proximal anastomosis in acute type a aortic dissection surgery.
J Cardiothorac Surg
January 2025
Cerrahpasa Medical Faculty, Department of Cardiovascular Surgery, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Objectives: Despite the advances in medicine, aortic dissection remains a cardiac surgery emergency with high mortality and morbidity rates. This study examined the effects of the Glue + Felt technique, which uses biological glue and felt to repair the proximal anastomotic site, on the outcomes of patients with acute type A aortic dissection.
Methods: A total of 108 patients who underwent surgery for acute type A aortic dissection at our clinic between 2007 and 2020 were included in the study.
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