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4D Printing Self-Sensing and Load-Carrying Smart Components.
Materials (Basel)
December 2024
Research Institute of Petroleum Exploration & Development, Beijing 100083, China.
In the past decade, 4D printing has received attention in the aerospace, automotive, robotics, and biomedical fields due to its lightweight structure and high productivity. Combining stimulus-responsive materials with 3D printing technology, which enables controllable changes in shape and mechanical properties, is a new technology for building smart bearing structures. A multilayer smart truss structural component with self-sensing function is designed, and an internal stress calibration strategy is established to better adapt to asymmetric loads.
View Article and Find Full Text PDFSelf-regulated efficient production of L-threonine via an artificial quorum sensing system in engineered Escherichia coli.
Microbiol Res
July 2024
Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China. Electronic address:
Imbalance in carbon flux distribution is one of the most important factors affecting the further increase in the yield of high value-added natural products in microbial metabolic engineering. Meanwhile, the most common inducible expression systems are difficult to achieve industrial-scale production due to the addition of high-cost or toxic inducers during the fermentation process. Quorum sensing system, as a typical model for density-dependent induction of gene expression, has been widely applied in synthetic biology.
View Article and Find Full Text PDFFunctional meniscus reconstruction with biological and biomechanical heterogeneities through topological self-induction of stem cells.
Bioact Mater
June 2024
Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing Key Laboratory of Sports Injuries, Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.
Article Synopsis
- Meniscus injuries are common in sports and contribute to osteoarthritis, highlighting the need for effective reconstruction methods.
- Current substitutes fail to mimic the natural meniscus's structure and function, prompting the development of a new tissue-engineered meniscus (TEM) with a unique microstructure.
- This innovation promotes proper stem cell differentiation and mimics the biomechanical properties of natural meniscus, showing promising results in healing and joint preservation after implantation in animal models.
A test of affect processing bias in response to affect regulation.
PLoS One
April 2022
Brain Imaging Research Center, Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
In this study we merged methods from machine learning and human neuroimaging to test the role of self-induced affect processing states in biasing the affect processing of subsequent image stimuli. To test this relationship we developed a novel paradigm in which (n = 40) healthy adult participants observed affective neural decodings of their real-time functional magnetic resonance image (rtfMRI) responses as feedback to guide explicit regulation of their brain (and corollary affect processing) state towards a positive valence goal state. By this method individual differences in affect regulation ability were controlled.
View Article and Find Full Text PDFPattern-sensitive patients with epilepsy use uncomfortable visual stimuli to self-induce seizures.
Epilepsy Behav
September 2021
Department of Human Neuroscience, Sapienza University of Rome, Italy. Electronic address:
Sensory stimuli can induce seizures in patients with epilepsy and predisposed subjects. Visual stimuli are the most common triggers, provoking seizures through an abnormal response to light or pattern. Sensitive patients may intentionally provoke their seizures through visual stimuli.
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