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First Reported Case of Pure Red Cell Aplasia Related to Sotorasib.
Intern Med
September 2024
Division of pulmonary medicine, Jichi Medical University Saitama Medical Center, Japan.
Article Synopsis
- A 64-year-old man with advanced lung adenocarcinoma and a KRAS mutation was treated with immune checkpoint inhibitors and later started on sotorasib.
- After one month on sotorasib, he developed severe anemia, indicated by low serum hemoglobin levels, high erythropoietin levels, and low reticulocyte counts.
- Bone marrow tests showed pure red cell aplasia, leading to the conclusion that sotorasib was the likely cause of the anemia after it improved upon stopping the medication.
Tackling Kinesiophobia in Chronic Shoulder Pain: A Case Report on the Combined Effect of Pain Education and Whole-Body Cryostimulation.
J Clin Med
April 2024
Research Laboratory in Biomechanics, Rehabilitation and Ergonomics, IRCCS, Istituto Auxologico Italiano, San Giuseppe Hospital, Piancavallo, 28824 Verbania, Italy.
Background: Chronic shoulder pain may cause significant functional disability and reduced psychosocial well-being. Detailed Case Description: In this case, we propose the use of pain neuroscience education and whole-body cryostimulation (WBC) to treat a 64-year-old woman with severe functional limitations and chronic right shoulder pain. The aim was to overcome kinesiophobia and improve her motor function, autonomy, and quality of life.
View Article and Find Full Text PDFPreventive service utilization among adults with cystic fibrosis covered by private insurance is comparable to the general population.
J Cyst Fibros
March 2024
Division of General Internal Medicine, Department of Internal Medicine, The Ohio State University College of Medicine, 3691 Ridge Mill Drive, Hilliard, Columbus, OH 43026, United States; Department of Internal Medicine, University of South Carolina School of Medicine Greenville, 1809 Wade Hampton Blvd, Ste. 120, Greenville, SC 29609, United States. Electronic address:
Background: As the life expectancy of the cystic fibrosis (CF) population is lengthening with modulator therapies, diligent age-appropriate screening and preventive care are increasingly vital for long-term health and wellbeing.
Methods: We performed a retrospective analysis comparing rates of receiving age- and sex-appropriate preventive services by commercially insured adult people with CF (PwCF) and adults without CF from the general population (GP) via the Truven Health MarketScan database (2012-2018).
Results: We captured 25,369 adults with CF and 488,534 adults from the GP in the United States.
Background: Pharmacists are likely to encounter questions from patients regarding medical cannabis (MC). This serves as an opportunity for pharmacists to provide reliable medical information about MC dosing, drug interactions, and impact on preexisting health conditions.
Objectives: This study examined changes in perceptions of the Arkansan community toward MC regulation and pharmacist involvement in MC dispensing after MC products became available in Arkansas.
Serotypes and Clonal Composition of Streptococcus pneumoniae Isolates Causing IPD in Children and Adults in Catalonia before 2013 to 2015 and after 2017 to 2019 Systematic Introduction of PCV13.
Microbiol Spectr
December 2021
Institut de Recerca Sant Joan de Deu, Hospital Sant Joan de Deu, Barcelona, Spain.
The goal of this study was to investigate the distribution of serotypes and clonal composition of Streptococcus pneumoniae isolates causing invasive pneumococcal disease (IPD) in Catalonia, before and after systematic introduction of PCV13. Pneumococcal strains isolated from normally sterile sites obtained from patients of all ages with IPD received between 2013 and 2019 from 25 health centers of Catalonia were included. Two study periods were defined: presystematic vaccination period (2013 and 2015) and systematic vaccination period (SVP) (2017 to 2019).
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