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Intractable reflex audiogenic epilepsy successfully treated by peri-insular hemispherotomy. | LitMetric

AI Article Synopsis

  • The case involves an infant born with infantile hemiplegia seizure syndrome (IHSS), presenting with a rare and difficult-to-control type of seizure called reflex audiogenic startle epilepsy.
  • A surgical procedure known as peri-insular hemispherotomy successfully eliminated the seizures, marking an important treatment milestone.
  • This instance of IHSS was linked to an iatrogenic brain injury incurred during a cesarean section, and the study evaluates existing literature on birth injuries and reflex epilepsy related to this novel case.

Article Abstract

We report a case of an infantile hemiplegia seizure syndrome (IHSS) that presented with intractable reflex audiogenic startle epilepsy which in itself is an uncommon form of seizure disorder. Peri-insular hemispherotomy provided complete seizure control. Also of particular interest was that this syndrome resulted from an iatrogenic brain injury sustained during the course of a caesarian section. We review the different mechanisms of birth injury reported in the literature and, discuss the physiopathogenesis of the hemispheric damage in this patient. We also review the literature on "reflex epilepsy" as it applies to this case. Intractable reflex audiogenic (startle) epilepsy in IHSS submitted to hemispherotomy has not previously been reported.

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Source
http://dx.doi.org/10.1016/j.seizure.2003.11.004DOI Listing

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