We report femtosecond visible pump, midinfrared probe, spectrally integrated experiments resolving the dynamics of CO in myoglobin upon photodissociation. Our results show a progressive change in absorption strength of the CO vibrational transition during its transfer from the heme to the docking site, whereas the vibrational frequency change is faster than our time resolution. A phenomenological model gives good qualitative agreement with our data for a time constant of 400 fs for the change in oscillator strength. Density-functional calculations demonstrate that indeed vibrational frequency and absorption strength are not linearly coupled and that the absorption strength varies in a slower manner due to charge transfer from the heme iron to CO.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1103/PhysRevLett.93.018102 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Design and evaluation of two proposed hybrid FCC-BCC lattice structures for enhanced mechanical performance.
Heliyon
January 2025
Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran.
Lattice structures are an innovative solution to increase the strength-to-weight ratio of a structure. In this study, two polymeric hybrid lattice structures-"FRB" (a heterogenous structure which is indeed a BCC structure reinforced by FCC unit cells dispersed in a way to form a chessboard pattern in each layer) and the "Multifunctional" (a homogenous structure whose unit cells are a combination of FCC and BCC unit cells where their central nodes are connected)-are proposed, fabricated via liquid crystal display 3D printing technique, and their mechanical characteristics are evaluated under quasi-static loading, experimentally and numerically. The results indicate a 15.
View Article and Find Full Text PDFImpact of extraction methods on the properties of Carica papaya pseudostem fibers from Cameroon used as reinforcement in biocomposites.
Heliyon
January 2025
Department of Mechanical Engineering, ENSET, University of Douala, P.O. Box: 1872, Douala, Cameroon.
Carica papaya pseudostems are widely available as biomass waste in Cameroon. These agricultural wastes can be effectively used as natural fibers in the manufacture of biocomposites. In this study Carica papaya fibers were extracted from papaya pseudostems by retting with water and an alkaline sodium hydroxide (NaOH) solution at different concentrations (2.
View Article and Find Full Text PDFThe synthesis of an iron tailings-based geopolymer with synergistic electromagnetic wave consumption property.
Environ Res
January 2025
School of Materials Science and Engineering, Fuzhou University, Fuzhou, Fujian, 350108, China; Zijin School of Geology and Mining, Fuzhou University, Fuzhou, Fujian, 350108, China; Fujian Key Laboratory of Green Extraction and High-value Utilization of Energy Metals, Fuzhou University, Fuzhou, Fujian 350108, China.
In this study, combination of wave absorption materials with different loss mechanisms are added into iron ore tailings-blast furnace slag (IOT-BFS) based geopolymers. The employed materials are hollow glass microsphere (HGM), carbon nanotubes (CNT) and carbonyl iron powder (CIP). Microstructures of the geopolymers are characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and concrete porous structure analyzer.
View Article and Find Full Text PDFExploring the interaction between calf thymus DNA and 11H-Indeno[1,2-b]quinoxalin-11-one Thiosemicarbazones: Spectroscopies and in vitro antitumor activity.
Int J Biol Macromol
January 2025
Analytical and Testing Center, Lingnan Normal University, Cunjin Road 29, Chikan District, Zhanjiang, Guangdong Province 524048, People's Republic of China.
Understanding the interactions between small molecules and calf thymus deoxyribonucleic acid (ctDNA) is critical for certain aspects of drug discovery. In this study, three 11H-indeno[1,2-b]quinoxalin-11-one thiosemicarbazones were synthesized and their interaction with ctDNA was examined through various spectroscopic techniques, including ultraviolet (UV) spectroscopy, fluorescence spectroscopy, and circular dichroism (CD) spectrum, and through physicochemical methods, including viscosity measurements. In addition, the effects of these thiosemicarbazone compounds 4a, 4b and 4c on several cancer cell lines were explored.
View Article and Find Full Text PDFExploring the drug delivery capabilities of NbC MXene functionalized with oxygen and fluorine: A DFT study.
J Mol Graph Model
January 2025
School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng, 224051, China. Electronic address:
MXenes quantum dots (QDs), including NbC, NbCO, and NbCF, are emerging materials with exceptional structural, electronic, and optical properties, making them highly suitable for biomedical applications. This study investigates the structural optimization, stability, electronic properties, and drug-loading potential of these QDs using fluorouracil (Flu) as a model drug. Structural analyses show that the functionalization of NbC with O and F atoms enhances stability, with binding energies (BEs) of 7.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!