After interaction with tracheal epithelial cells, Bordetella pertussis induces the secretion of interleukin-6. This secretion is dependent on the expression of adenylate cyclase-hemolysin by the bacterium but not on the expression of other characterized bacterial toxins or adhesins. This finding confirms the important role of adenylate cyclase-hemolysin in the pathogenicity of the bacterium.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC517437 | PMC |
| http://dx.doi.org/10.1128/IAI.72.9.5530-5533.2004 | DOI Listing |
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