Objective: To study the clinical and imaging features of thyroid carcinoma with bone metastasis and evaluate the importance of the imaging diagnosis in such cases.
Methods: A retrospective analysis was performed on the results of X-ray and CT examinations of 10 pathologically confirmed patients (including 2 men and 8 women aged from 40 to 89 years with a mean age of 61 years) with thyroid carcinoma with bone metastasis.
Results: Thyroid carcinoma was latent in terms of its disease history. In these cases, the primary tumors were identified after the bone metastasis in 3 cases, and the bone metastasis occurred on the basis of the primary lesions or the thyroid gland nodules in 7 cases. Thyroid carcinoma with bone metastasis occurred mostly in the skeleton of the upper body, characterized mainly by cystic expansion of the bone tissue destruction causing extensive patchy map-like bone defects.
Conclusion: Bone metastasis is common in thyroid carcinoma, manifested typically by bone lysis with occasional osteogenic metastasis.
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