AI Article Synopsis

  • Persistent hyperinsulinemic hypoglycemia of infancy (PHHI) is a rare but serious condition characterized by low blood sugar levels due to high insulin production.
  • Early diagnosis and surgical intervention, specifically near total pancreatectomy, are crucial for effective treatment and recovery.
  • Two case studies demonstrate successful outcomes post-surgery, with both patients maintaining normal blood sugar levels, although one needs pancreatic enzyme supplements for digestion.

Article Abstract

Persistent hyperinsulinemic hypoglycemia of infancy (PHHI) or nesidioblastosis is a rare condition presenting with severe hypoglycemia. Prompt diagnosis and early pancreatectomy can save many of them, in spite of the magnitude of surgery. We present two cases in which near total pancreatectomy was performed with favourable outcome. Both patients are normoglycemic, with one requiring pancreatic enzyme supplements.

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