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In vivo confocal microscopy (IVCM) is a non-invasive imaging technique used to visualize the layers of the cornea and conjunctiva in real time. In patients with atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC), this technology can be useful in diagnosing and monitoring the disease, as well as evaluating the efficacy of treatments. IVCM can reveal subclinical abnormalities in the corneal and conjunctival epithelium such as inflammatory cell infiltrates and tissue damage, which can provide insight into the pathogenesis of AKC.

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Purpose: To study the epidemiology and clinical presentation of allergic eye diseases (AEDs) and Vernal Keratoconjunctivitis (VKC).

Methods: A cross-sectional- cum-cohort study was conducted in rural and urban areas in different geographical locations (plains, hilly, high-altitude and coastal) in India. Children (5-15 years) were included, information on exposure to environmental factors gathered, participants screened for AED and VKC on torch light, followed by a comprehensive eye examination.

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Allergic conjunctivitis (AC) is characterized by inflammatory responses in the conjunctiva and is often complicated by atopic dermatitis and mechanical irritation. Vernal keratoconjunctivitis (VKC), a severe subtype of AC, presents unique challenges in its diagnosis and management, particularly in pediatric patients. This case report describes an eight-year-old girl with VKC who exhibited poor adherence to a prescribed regimen of 0.

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Purpose: To conduct a systematic review and meta-analysis to provide an outline of available data on the association between serum vitamin D levels and vernal keratoconjunctivitis (VKC) and to determine the possible relationship in children.

Methods: Systematic research on all articles published until July 2023 was conducted in PubMed, SCOPUS, Web of Science, and Embase. All observational-analytical studies that measured vitamin D levels in patients with VKC were included.

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[Efficacy of biologics for severe asthma on allergic comorbidities].

Rev Mal Respir

November 2024

Service de pneumologie et centre de référence des maladies pulmonaires rares, AP-HP Nord, hôpital Bichat, 75018 Paris, France; Inserm UMR1152, université Paris Cité, Paris, France.

Article Synopsis
  • Some treatments called biologics can help people with severe asthma and other allergic diseases like skin issues and food allergies.
  • Dupilumab has been shown to work well for skin problems and has been approved, while Omalizumab helps with allergies but isn't approved for that use yet.
  • There are promising ideas about combining biologic therapy with other treatments for allergies, but more research is needed to confirm if they really work.
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