Background: Assessment of pulmonary function may be done by several procedures, such as spirometric and flow metric ones.
Objective: To obtain a peak expiratory flow rate (PEFR) percentilar curve in healthy schoolchildren of both sexes of Merida, Yucatan, Mexico.
Material And Methods: We carried out a transversal and observational study in schoolchildren between 6 and 12 years old of both sexes. They were evaluated by a demographic questionnaire that included age, weight, height and health status, and then the PEFR was assessed using a mini-Wright Peak Flow Meter recording the highest of the three numbers achieved.
Results: We included 621 healthy schoolchildren between 6 and 12 years old of both sexes, 321 girls and 300 boys, of two schools that were selected by random sampling. The media age was 9 +/- 2 years old, height 128 +/- 10 cm, weight 30.34 +/- 9.75 kg, corporal surface 1.049 +/- 0.22 m2, and PEFR 293.72 +/- 66 L/min. When we compared the PEFR with age, height and weight, we saw that height was a more reliable predictor than age or weight, since higher values of R were obtained. There was not a significant difference of PEFR between boys and girls.
Conclusions: Our results show that the pulmonary function values increase proportionally to height, which showed the higher correlation to FEM.
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Alzheimers Dement
December 2024
National Center for Neurological Disorders, Shanghai, China.
Background: Whether lung function prospectively affects cognitive brain health independent of their overlapping factors remains largely unknown. This study aimed to investigate the longitudinal association between decreased lung function and cognitive brain health and to explore underlying biological and brain structural mechanisms.
Method: This population-based cohort included 43,1834 non-demented participants with spirometry from the UK Biobank.
Laryngoscope Investig Otolaryngol
February 2025
Otorhinolaryngology and Head and Neck surgery Unidade Local de Saúde de Santo António Porto Portugal.
Background And Objective: Septoplasty and turbinate reduction surgery (STR) is hypothesized to affect pulmonary function by modifying airway dynamics. This study investigates the impact of STR-mediated improvements in nasal patency on pulmonary function tests (PFTs).
Methods: In a prospective analysis, 37 adult patients undergoing STR were enrolled.
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
December 2024
Department of General Medicine, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Objective: To evaluate the efficacy and safety of magnesium sulfate in the treatment of acute severe asthma in adults.
Methods: Literature searches were conducted on PubMed, Cochrane, CNKI, VIP and Wanfang databases to screen randomized controlled trial (RCT) of magnesium sulfate in the treatment of acute severe asthma in adults, starting from the establishment of the database and ending on May 22, 2024. The control group received conventional treatment.
Respir Res
January 2025
School of Engineering, University of Warwick, Coventry, CV4 7AL, UK.
Introduction And Objectives: High flow nasal cannula (HFNC) therapy is an increasingly popular mode of non-invasive respiratory support for the treatment of patients with acute hypoxemic respiratory failure (AHRF). Previous experimental studies in healthy subjects have established that HFNC generates flow-dependent positive airway pressures, but no data is available on the levels of mean airway pressure (mP) or positive end-expiratory pressure (PEEP) generated by HFNC therapy in AHRF patients. We aimed to estimate the airway pressures generated by HFNC at different flow rates in patients with AHRF, whose functional lung volume may be significantly reduced compared to healthy subjects due to alveolar consolidation and/or collapse.
View Article and Find Full Text PDFPhysiol Rep
January 2025
Department of Kinesiology, James Madison University, Harrisonburg, Virginia, USA.
To assess the impact of thoracic load carriage on the physiological response to exercise in hypoxia. Healthy males (n = 12) completed 3 trials consisting of 45 min walking in the following conditions: (1) unloaded normoxia (UN; FO:20.93%); (2) unloaded hypoxia (UH; FO:~13.
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