[Claritromycin in the modern schemes of eradication of helicobacter infection in patients with ulcer disease].

Out of the fifty patients with duodenal peptic ulcer having received conventional dosages of ranitidin (phamotidin) combined with Denol, metronidazole, and/or tetracycline over two weeks the relapse of the illness within one year occured in 22 percent. Of these, 44 patients had a culture isolated the sensitivity of which to antibiotics was studied with the aid of standard disks or end-point dilutions. 38.7 percent of strains of bacteria were found out to be insensitive to tetracycline, 6.8 percent--to metronidazole, 2.3 percent--to amoxicylline, and no strain was sensitive to claritromycin. The repeated treatment of patients with recurrences of the illness with a combination of omeprazole (20 mg two times daily), amoxicylline (1000 mg twice per day), and claritromycin (500 mg twice per day) for up to 7 days showed no infection in the patients.