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Moderated 252Cf neutron energy spectra in brain tissue and calculated boron neutron capture dose. | LitMetric

Moderated 252Cf neutron energy spectra in brain tissue and calculated boron neutron capture dose.

Appl Radiat Isot

Department of Radiation Oncology, Tufts-New England Medical Center #246, Tufts University School of Medicine, 750 Washington Street, Boston, MA 02111, USA.

Published: November 2004

While there is significant clinical experience using both low- and high-dose (252)Cf brachytherapy, combination therapy using (10)B for neutron capture therapy-enhanced (252)Cf brachytherapy has not been performed. Monte Carlo calculations were performed in a brain phantom (ICRU 44 brain tissue) to evaluate the dose enhancement predicted for a range of (10)B concentrations over a range of distances from a clinical (252)Cf source. These results were compared to experimental measurements and calculations published in the literature. For (10)B concentrations

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http://dx.doi.org/10.1016/j.apradiso.2004.05.017DOI Listing

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