[Microkeratome-assisted deep lamellar endothelial keratoplasty].

Zhonghua Yan Ke Za Zhi

Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.

Published: March 2004

AI Article Synopsis

  • The study aimed to investigate the effectiveness, surgical principles, clinical outcomes, and complications of microkeratome-assisted deep lamellar endothelial keratoplasty (DLEK) in patients with bullous keratopathy.
  • DLEK was performed on six patients, with some undergoing additional procedures like vitrectomy and lens implantation, and they were followed for 6 to 9 months post-surgery.
  • Results showed significant improvement in vision for most patients, with no serious complications reported, suggesting DLEK could be a viable alternative to traditional penetrating keratoplasty (PKP), though further research is needed for confirmation.

Article Abstract

Objective: To observe the indication, surgical principle, clinical results and complications of microkeratome-assisted deep lamellar endothelial keratoplasty (DLEK).

Methods: DLEK was performed in six patients with bullous keratopathy. One of the six patients underwent DLEK combined with vitrectomy under temporary artificial corneal and intraocular foreign-body removal. Another underwent DLEK combined with vitrectomy and posterior chamber intraocular lens implantation. The patients were followed up for 6 approximately 9 months.

Results: The postoperative best-corrected visual acuity showed clear improvement in 5 cases. Endothelial cell density averaged (2481 +/- 212) cells/mm(2). Pachymetry averaged (549 +/- 61) micro m. Astigmatism averaged (2.04 +/- 1.19) D. No serious complication was found.

Conclusion: DLEK is an alternative choice for PKP. It may offer further advantages over conventional PKP surgery, and could serve as a surgical technique in endothelial keratoplasty. A long-term follow-up in a larger patient population is needed to confirm our initial results.

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