Silver(I) oxide mediated selective monoprotection of diols in pyranosides.

J Org Chem

The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science, Peking University, Xue Yuan Road #38, Beijing 100083, P. R. China.

Published: August 2004

The reaction of 4, 6-O-benzylidene-d-pyranosides with a stoichiometric amount of TsCl, AcCl, and BzCl in the presence of silver(I) oxide and a catalytic amount of potassium iodide led to monosubstituted derivatives in high regioselectivity and in good yields.

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo0497252DOI Listing

Publication Analysis

Top Keywords

silveri oxide
8
oxide mediated
4
mediated selective
4
selective monoprotection
4
monoprotection diols
4
diols pyranosides
4
pyranosides reaction
4
reaction 6-o-benzylidene-d-pyranosides
4
6-o-benzylidene-d-pyranosides stoichiometric
4
stoichiometric amount
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!