Purpose: To evaluate the efficacy of topical mitomycin C (MMC) 0.02% in treating conjunctival intraepithelial neoplasia (CIN).
Methods: Three patients with CIN were treated with topical MMC 0.02%. Our follow-up period was twelve months (range 8-18 months).
Results: CIN was resolved in all three cases without modifying the normal corneal and conjunctival architecture.
Conclusions: Topical MMC 0.02% four times daily during two weeks is a useful alternative tool for the surgical management of CIN.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4321/s0365-66912004000800004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Fundus Curvature as a Clinical Marker for Posterior Staphyloma Based on Widefield Optical Coherence Tomography.
Am J Ophthalmol
December 2024
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China. Electronic address:
Purpose: To investigate the ability to quantify fundus curvature and detect posterior staphyloma using widefield optical coherence tomography (OCT).
Design: Cross-sectional diagnostic evaluation.
Subjects And Participants: 205 highly myopic eyes of 205 participants.
5-Methyltetrahydrofolate and aqueous extract of () ameliorate diabetes and associated complications in STZ-induced diabetic rats.
3 Biotech
January 2025
Plant Cell Biotechnology (PCBT) Department, Central Food Technological Research Institute (CFTRI), Mysuru, 570 020 India.
Unlabelled: The present study evaluated the effects of 5-methyltetrahydrofolate (5-MTHF) and aqueous extract on diabetes. An in silico docking study with select bioactive compounds showed strong binding affinities of folates with glucose metabolism-related proteins. In vitro assay showed 5-MTHF's superior inhibitory activity on alpha-amylase compared to folic acid.
View Article and Find Full Text PDFFrequency of Sleep Disorders in Rheumatoid Arthritis Patients.
Cureus
October 2024
Pulmonology, Khalifa Gul Nawaz Teaching Hospital, Bannu Medical College Medical Teaching Institute, Bannu, PAK.
Article Synopsis
- The study examines how sleep disturbances affect individuals with rheumatoid arthritis (RA), focusing on prevalence and links to patient demographics and disease severity.
- Conducted from January to December 2023, the research involved 385 RA patients and utilized established sleep assessment tools, revealing that 75.32% of participants reported poor sleep quality.
- Findings indicate significant associations between insomnia and moderate disease activity, as well as sleep apnea with low disease activity, underscoring the need for enhanced management strategies for sleep issues in RA patients.
Risk factors for hospitalisation in community-dwelling pre-frail and frail older people: results of a longitudinal study.
BMC Geriatr
October 2024
Emergency Department, Erasmus MC, Rotterdam, The Netherlands.
Background: Older adults account for a large proportion of hospital admissions. In this study we aim to bridge a gap between medical and psychosocial factors in predicting hospitalisation.
Methods: Demographic and social characteristics of community-dwelling pre-frail and frail older people were collected by questionnaires every six months during a two year follow-up.
Choroid Involvement Secondary to Optic Disc Pit Maculopathy: OCT Analysis and Evolution After Surgical Treatment.
Am J Ophthalmol
February 2025
From the Ophthalmology Department (M.M.C., F.B., F.G., E.C., S.R.), "Fondazione Policlinico Universitario A. Gemelli, IRCCS", Rome, Italy; Ophthalmology Department (M.M.C., F.B., F.G., E.C., T.C., S.R.), Catholic University "Sacro Cuore", Rome, Italy; Consiglio Nazionale delle Ricerche (S.R.), Istituto di Neuroscienze, Pisa, Italy.
Purpose: To assess choroidal changes associated to optic disc pit maculopathy (ODP-M) and their evolution after surgical treatment.
Design: Multicentric retrospective case series.
Methods: An analysis of 42 patients affected by unilateral ODP-M undergoing surgical treatment between 2013 and 2023 was conducted.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!