Concise asymmetric synthesis of (-)-sparteine.

Chem Commun (Camb)

Department of Chemistry, University of York, Heslington, York, UK.

Published: August 2004

A six-step asymmetric synthesis of natural (-)-sparteine from ethyl 7-iodohept-2-enoate is reported, involving a connective Michael addition of an amino ester-derived enolate to an alpha,beta-unsaturated amino ester.

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Source
http://dx.doi.org/10.1039/b406632dDOI Listing

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