Abstract Congenital cutaneous papillomas were identified in five foals. Age at diagnosis ranged from 305 days' gestation to 2 days of age. Breeds were thoroughbred (2), standard-bred (1), warmblood (1) and paint (1). Two were female, one was male and the gender of two cases was not specified. Masses were pedunculated with a roughened, wart-like (verrucous) or a smoother, cauliflower-like surface. Masses occurred as single lesions on the forelimb, lip and face, or as multiple lesions on the trunk. Histological features included relatively uniform epidermal papillary hyperplasia with variable melanin pigment within basal layers and vacuolization of keratinocytes in all layers, but with no evidence of nuclear or cytoplasmic changes (koilocytes) characteristic of viral infection. One case showed epidermal proliferation with proliferation of pilosebaceous units. Results of immunohistochemical studies for the detection of papillomavirus antigens were negative in all cases. These results suggest that equine congenital papilloma may be a hamartomatous lesion (epidermal nevus) and not a viral-induced growth.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-3164.2004.00395.xDOI Listing

Publication Analysis

Top Keywords

equine congenital
8
congenital papilloma
8
papilloma pathological
4
pathological findings
4
findings papillomavirus
4
papillomavirus immunohistochemistry
4
immunohistochemistry cases
4
cases abstract
4
abstract congenital
4
congenital cutaneous
4

Similar Publications

Background: Supernumerary digits, or polydactyly, have been described in various species including humans, wild and domestic animals. In horses, it represents the most common congenital limb malformation, which has only been described in isolated cases or nuclear families. Molecular aetiology has not been reported.

View Article and Find Full Text PDF

Aim: This study aims to determine how often Achilles tenotomy is performed on patients who have congenital talipes equinovarus (CTEV) and have been managed with Ponseti serial casts.

Materials And Methods: This prospective cohort study took place from November 2021 to May 2023 in the orthopedic unit of Hayatabad Medical Complex, Peshawar, Pakistan. About 38 pediatric patients with CTEV, who received treatment in the form of Ponseti casting, were enrolled in the study.

View Article and Find Full Text PDF

Immunodeficiencies in Foals.

Vet Clin North Am Equine Pract

December 2024

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California - Davis, 1 Garrod Drive, Davis, CA 95616, USA. Electronic address:

Knowledge of immunodeficiencies is crucial to neonatal medicine, in that they predispose to sepsis in the newborn and neonatal foal, as well as recurrent infections in older foals. The most common immunodeficiency in newborn and neonatal foals is failure of passive transfer, which is an example of an acquired immunodeficiency. Congenital or developmental immunodeficiencies may be transient or permanent, and can either affect the cell-mediated or humoral arms of immunity, and in some cases both.

View Article and Find Full Text PDF

Bilateral congenital cystic eye with intraocular tissue differentiation in a horse.

J Vet Med Sci

January 2025

Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.

Congenital cystic eye (CCE) is a rare congenital ocular disease, which has been suggested to be caused by problems with optic vesicle invagination. This is characterized by the formation of intraorbital cystic lesions lined by undifferentiated neuroepithelium. However, cases involving ocular structures with varying degrees of differentiation have also been reported as CCE in humans and animals.

View Article and Find Full Text PDF

Hydroallantois in a mare associated with schistosomus and unilateral ovarian agenesis in the fetus.

J Equine Vet Sci

January 2025

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, United States.

Article Synopsis
  • Hydropsical conditions in domestic animals involve abnormal fluid buildup, often linked to issues like placentitis or fetal abnormalities, and can pose a medical emergency for pregnant mares.
  • A case study featured a 9-year-old Quarter mare with hydroallantois at 271 days of gestation, resulting in the birth of a non-viable foal with severe congenital defects.
  • The situation required swift medical intervention, which included fluid drainage and pregnancy termination, ultimately highlighting the necessity for early diagnosis and management of such conditions in horses.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!