Objective: To select the most intense light source that penetrates tissues and is safe for fetal biophysical testing
Study Design: A 3-step series of experiments was undertaken using a digital light meter (Extech Light Probe Meter, Extech Instruments, Waltham, Massachusetts). First, the density of light through a light filter was compared between the sun and 4 commercially available light sources. Second, penetration of light through the abdominal subcutaneous tissue (3-4 cm thick) of 6 pigs was compared between these light sources. Last, the skin reaction to the preferred light source and the distance in penetrating the uterine cavity were assessed in 50 pregnant women.
Results: Light emitted from a halogen bulb was significantly more intense than from a photographic flash, krypton bulb or penlight. Maximal intensity was gained with the light source placed against the skin. The halogen bulb penetrated a pig's abdominal wall more than the photographic flash or krypton bulb. The thickness of a pig's abdominal wall is similar to the distance in pregnant humans near term from the skin to the uterine cavity. No thermal injury or discomfort to the skin was observed for exposures <10 seconds.
Conclusion: The halogen bulb was safe, penetrated tissues most effectively and was the best light source for fetal biophysical testing.
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ACS Appl Mater Interfaces
January 2025
School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
Photobiomodulation (PBM) is considered an effective and safe therapeutic modality in supporting the treatment of complications from a global pandemic-diabetes. In this study, PBM therapy is investigated to accelerate wound healing in diabetic mice (DM), under the combined biological effects of red light from a red organic light-emitting diode (ROLED) and near-infrared (NIR) light from an NIR conversion film (NCF) with dispersed CuInS/ZnS quantum dots (QDs). The QD concentration and the NCF structure were optimized to maximize the optical properties and mechanical stability.
View Article and Find Full Text PDFBr J Anaesth
January 2025
Light and Health Research Center, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:
Photodiagnosis Photodyn Ther
January 2025
Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran. Electronic address:
Background: Candida albicans is the primary cause of vulvovaginal candidiasis, a worldwide health concern for women. The use of supplemental methods, such as antimicrobial photodynamic therapy (aPDT) and probiotics, was promoted by the ineffectiveness of the existing antifungal drugs.
Methods: This study examines the combined effects of probiotics (Bacillus and Enterococcus isolated from the fermented pickles) and PDT (using red laser (655 nm, 18 J/cm) as a light source and methylene blue dye (30 mg/mL) as a photosensitizer) on the in vitro virulence activity of C.
Biosens Bioelectron
December 2024
Biophotonic Nanosensors Laboratory, Centro de Física Aplicada y Tecnología Avanzada (CFATA), Universidad Nacional Autónoma de México (UNAM), Querétaro, 76230, Mexico. Electronic address:
Smartphone-based colorimetric (bio)sensing is a promising alternative to conventional detection equipment for on-site testing, but it is often limited by sensitivity to lighting conditions. These issues are usually avoided using housings with fixed light sources, increasing the cost and complexity of the on-site test, where simplicity, portability, and affordability are a priority. In this study, we demonstrate that careful optimization of color space can significantly boost the performance of smartphone-based colorimetric sensing, enabling housing-free, illumination-invariant detection.
View Article and Find Full Text PDFSci Total Environ
January 2025
Faculty of Business Administration, Memorial University of Newfoundland, St. John's, NL A1B 3X9, Canada.
Industrial, agricultural, and natural pollution pose a critical problem for the Prairie provinces of Canada, with significant environmental and health concerns. This study addresses a critical knowledge gap by assessing the cumulative impacts of pollutants in the Prairie region, which hosts 40 % of the Canada's indigenous population, often living near these pollution sources. By innovatively integrating Sentinel-5P satellite data, Google Earth Engine, ArcGIS, and Python, we show the trends in CO, NO₂, HCHO, SO₂, and aerosols from 2019 to 2023 at high resolution for the entire region, which sheds new light on the dynamics that operate beyond conventional air quality monitoring.
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