[Impact of intraoperative autotransfusion on RBC's in vivo half-life].

Objective: To explore the changes of in vivo half-life of processed erythrocytes following intraoperative autotransfusion(IAT) in off-pump coronary artery bypass grafting(CABG).

Methods: From November 2003 to January 2004,20 consecutive patients undergoing scheduled off-pump CABG were randomly divided into experimental group and control group. Intra-operative autotransfusion was used in the experimental group. The samples were drawn immediately after the saving procedure in the experimental group and immediately after anesthesia introduction through central venous catheter in the control group. A single isotope technique ((51)Cr) was used to determine in vivo half-life of the RBCs in the two groups.

Results: There was no significant difference in in vivo half-life between the two groups.

Conclusion: The in vivo half life of processed erythrocytes following intraoperative autotransfusion ZITI-3000 Cell saving system has not changed significantly in off-pump CABG.