Four clonally related Escherichia coli strains were isolated successively from bile duct of a girl suffering from sclerosing cholangitis. One of them, selected after an imipenem-containing regimen, was resistant to carbapenems and to broad-spectrum cephalosporins due to a plasmid-mediated cephalosporinase, CMY-2, and the lack of outer membrane proteins OmpF and OmpC.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC497580 | PMC |
http://dx.doi.org/10.1128/JCM.42.8.3831-3833.2004 | DOI Listing |
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