Background: Severe intraoperative bleeding cannot always be controlled by standard surgical techniques. We recently reported a new technique to repair serious vascular injury using a free graft of omentum or rectus abdominus fascia as an overlay autogenous tissue (OAT) patch in the experimental sheep model. We now describe the successful clinical use of this patch in three patients.
Case Reports: Radical surgery was performed on three patients with pelvic malignancy with resulting uncontrollable bleeding from the internal iliac vein, pelvic side wall and paravaginal venous plexuses, respectively. Hemostasis was secured using an OAT patch made of abdominus rectus fascia in two cases and appendix epiploicae as an omental substitute in the other.
Discussion: The utility of the OAT patch is described in three different clinical situations. It is suggested that this technique may be especially useful to gynecologic oncologists when standard surgical techniques fail to control bleeding or there is limited access to the site of injury.
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http://dx.doi.org/10.1016/j.ygyno.2004.06.007 | DOI Listing |
Int Ophthalmol
December 2024
Genetics Department, Institute of Ophthalmology "Conde de Valenciana", Mexico City, Mexico.
Purpose: Description of retinal phenotype by structural and functional testing, ornithine plasma levels and mutational data of OAT gene in patients with Gyrate Atrophy (GA).
Methods: Ophthalmologic examination, fundus photography (CFP), autofluorescence (FAF), spectral-domain optical coherence tomography (SD-OCT), Goldmann perimetry (GP), full-field electroretinogram (ffERG) and chromatic perimetry (CP) testing were performed. Ornithine plasma levels were measured.
Ophthalmol Retina
October 2024
LV Prasad Eye Institute, Kalam Anji Reddy Campus, Anant Bajaj Retina Institute, Srimati Kanuri Santhmma Centre for Vitreoretinal Diseases, Hyderabad, India.
Objective: To profile a cohort of gyrate atrophy patients classified by widefield retinal imaging and correlate the structural, biochemical, and functional characteristics.
Design: Retrospective observational cohort study.
Participants: Sixty-five patients (129 eyes) with gyrate atrophy.
Drug Alcohol Rev
October 2024
Drug and Alcohol Clinical Services, Hunter New England Local Health District, Newcastle, Australia.
Int J Drug Policy
October 2024
British Columbia Centre on Substance Use, Vancouver, BC, Canada; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada. Electronic address:
Objectives: Many people who use drugs in the United States and Canada continue to access the contaminated unregulated drug supply, resulting in the ever-escalating overdose epidemic. In Canada, even in areas where healthcare providers are authorized to prescribe alternatives to the unregulated supply (e.g.
View Article and Find Full Text PDFArch Soc Esp Oftalmol (Engl Ed)
September 2024
Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain. Electronic address:
Gyrate atrophy of the choroid and retina (GACR) is a rare autosomal recessive disease characterised by elevated plasma ornithine levels due to deficiency of the enzyme ornithine aminotransferase (OAT). The accumulation of this amino acid in plasma leads to the development of patches of chorioretinal atrophy in the peripheral retina extending into the macular area. Patients usually present with night blindness followed by constriction of the visual field and, finally, decreased central vision and blindness.
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