Similar to higher vertebrates, neoplasia is not an uncommon disease in fishes, which are the largest group of vertebrates. However,neoplasia in fishes is generally a benign condition with relatively few exceptions of malignant disease. The objective of this discussion is to provide an overview of neoplasia and the various neoplastic disease conditions in fishes according to organ system,including the few neoplasms of species that are familiar to the aquatic animal or exotic animal practitioner. The discussion also considers the various nonneoplastic lesions in fishes that may be confused with neoplasms, and treatment of neoplastic disease in fishes that is generally restricted to surgical intervention.
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http://dx.doi.org/10.1016/j.cvex.2004.04.012 | DOI Listing |
The first clinical trial of zebrafish embryos acting as cancer "avatars" will start soon.
View Article and Find Full Text PDFBiomed Chromatogr
February 2025
Department of Pharmacy, Lianyungang Affiliated Hospital of Nanjing University of Chinese Medicine, Lianyungang, China.
Choerospondias axillaris is a medicinal plant used for treating coronary heart disease (CHD) due to its broad spectrum of anti-inflammatory activities. Cyclooxygenase 2 (COX-2) and lipoxygenase 5 (5-LOX) were immobilized on magnetic nanoparticles for selective ligand-extraction of these two enzymes present in C. axillaris.
View Article and Find Full Text PDFBackground: Alzheimer's Disease (AD) is the leading form of senile dementia, affecting ∼6 million Americans and having a national economic impact of $321 billion, numbers expected to double by 2050. The major pathological hallmarks of AD include Amyloid Beta (Aβ) plaques and Tau neurofibrillary tangles (NFT). The first goal of this research was to develop novel forms of carbon dots (CD) using various precursors.
View Article and Find Full Text PDFBackground: Alzheimer's Disease (AD) is a neurodegenerative disorder whose pathological hallmarks include tau and amyloid beta aggregation, a phenomenon that has been linked to inflammation and degradation of brain tissue. Prior data published in the Wang lab suggests that carbon dots (CDs) synthesized from citric acid and urea can inhibit aggregation. We sought to characterize the inhibitory effects of a new class of CDs synthesized from varied ratios of Congo red and citric acid.
View Article and Find Full Text PDFDis Aquat Organ
January 2025
ICAR Research Complex for NEH Region, Umiam, Meghalaya PIN-793103, India.
The present study evaluated the immunomodulatory and disease resistance-enhancing effects of dietary supplementation of Withania somnifera root powder in Labeo rohita (22.10 ± 3.30 g, 12.
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