Background: Hypertension is the commonest non-communicable disease in our environment. Left ventricular hypertrophy is quite prevalent among this category of patients.
Methods: An endeavour was therefore made to review the literature on left ventricular hypertrophy in hypertension using MEDLINE and bibliographic searches for English language studies.
Results: The epidemiology, pathogenesis, molecular mechanism, pathophysiology, pathology and diagnosis of left ventricular hypertrophy in hypertension were presented. Effect of left ventricular hypertrophy on morbidity and mortality and the probable consequence of its regression were also discussed.
Conclusion: Left ventricular hypertrophy in hypertension can be detected through an avalanche of diagnostic modalities and criteria. It carries not just management but also prognostic implications.
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Appl Nurs Res
April 2025
Training Office, IRCCS Policlinico San Donato, Milano, Italy.
Background: Self-care is essential for patient with chronic conditions such as heart failure. Self-care facilitates adaptation in patients with a Left Ventricular Assist Device (LVAD), improving their outcomes and preventing complications. Currently, no studies provide an overview of self-care in people with LVADs.
View Article and Find Full Text PDFDtsch Med Wochenschr
March 2025
Cardiogenic shock is not a singular disease but rather a complex syndrome - characterized by systemic hypoperfusion, elevated intracardiac pressures, and insufficient cardiac output due to various possible underlying causes, leading to an acute, life-threatening, and critical condition.Significant advancements have been made in recent years in understanding the epidemiology, clinical course, phenotyping, hemodynamics, and the standardized classification of disease severity. However, progress in therapeutic interventions aimed at improving prognosis has been comparatively limited, with only a few therapies demonstrating significant evidence in randomized controlled trials.
View Article and Find Full Text PDFJ Leukoc Biol
March 2025
Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Berlin, Germany.
Age is an important risk factor for cardiovascular diseases (CVD) and associated with a systemic, low-grade inflammation, so called "inflammaging". We aimed to investigate the impact of age and sex on the inflammatory markers S100A9 and components of the NLRP3 inflammasome at an early stage in the aging process, using mature adult and middle-aged/perimenopausal mice. Given the importance of the cardiosplenic axis in heart failure, the spleen was analyzed in addition to the left ventricle and cardiac fibroblasts.
View Article and Find Full Text PDFAm J Med Sci
March 2025
From the Digestive Disease Research Center, Medical University of South Carolina, Charleston, SC. Electronic address:
Background: Angiodysplasias commonly develop in patients with left ventricular assist devices (LVADs) and often bleed recurrently. Whether octreotide reduces the burden of angiodysplasia or the frequency of bleeding in these patients is controversial. Hence, we aimed to study the effect of long-acting octreotide on angiodysplasia bleeding in LVAD patients.
View Article and Find Full Text PDFTrends Cardiovasc Med
March 2025
Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy; Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. Electronic address:
Angina pectoris, a primary manifestation of ischemic heart disease, imposes a significant clinical and economic burden globally. This review highlights recent advancements in the management of angina, emphasizing a patient-centred approach that integrates pharmacological, interventional, and lifestyle strategies to reduce cardiovascular risk and improve patient outcomes. For obstructive coronary artery disease, optimal medical therapy represents the cornerstone of treatment.
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