Background: Studies relating periodontal disease to coronary heart disease (CHD) have provided equivocal results using tooth loss and/or clinical signs of periodontal disease as measures of periodontal exposure.
Methods: The purpose of this cross-sectional study was to evaluate the relationship of tooth loss and periodontitis to prevalent CHD at the Atherosclerosis Risk in Communities (ARIC) visit 4 using both tooth loss and clinical signs of disease in a population-based sample of 8,363 men and women aged 52 to 75 years from four U.S. communities. Each subject participated in a complete periodontal examination, assessment of missing teeth, assessment of prevalent CHD, and a number of laboratory tests and questionnaires. High attachment loss was defined as > or = 10% of sites with attachment loss > 3 mm and high tooth loss was defined as fewer than 17 remaining teeth.
Results: Individuals with both high attachment loss and high tooth loss (odds ratio [OR] 1.5, 95% confidence interval [CI] 1.1 to 2.0) and edentulous individuals (OR 1.8, CI 1.4 to 2.4) had elevated odds of prevalent CHD compared to individuals with low attachment loss and low tooth loss, while controlling for a number of traditional risk factors for CHD.
Conclusions: These results suggest that tooth loss and periodontal disease are associated with prevalent CHD, but only when both are present. The weaker relationships between periodontal disease and CHD that have been found among older adults may be due to older adults having fewer teeth. Future longitudinal studies should be designed to ascertain the cause of tooth loss during follow-up.
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http://dx.doi.org/10.1902/jop.2004.75.6.782 | DOI Listing |
Genome Biol Evol
January 2025
ISEM, Univ. Montpellier, CNRS, IRD, Montpellier, France.
Ant-eating mammals represent a textbook example of convergent evolution. Among them, anteaters and pangolins exhibit the most extreme convergent phenotypes with complete tooth loss, elongated skulls, protruding tongues, and hypertrophied salivary glands producing large amounts of saliva. However, comparative genomic analyses have shown that anteaters and pangolins differ in their chitinase acidic gene (CHIA) repertoires, which potentially degrade the chitinous exoskeletons of ingested ants and termites.
View Article and Find Full Text PDFEur J Med Res
January 2025
Basel Academy for Quality and Research in Medicine, Steinenring 6, 4051, Basel, Switzerland.
Background: Heterogeneous results are to be expected when multiple raters diagnose whether the dentine of a tooth with erosive tooth wear (ETW) is exposed or not. Identification of notions (fundamental concepts and understanding) about the diagnostic problem shared by groups of raters can be helpful to develop guidelines and to optimize teaching and calibration procedures. We aim to illustrate how clusters of raters with a common notion can be identified and how first insights about the notions can be obtained.
View Article and Find Full Text PDFJ Prosthodont
January 2025
Department of Restorative Dental Science, College of Dentistry, University of Ha'il, Ha'il, Saudi Arabia.
Purpose: To investigate how varying ferrule heights and the number of glass fiber posts affect fracture resistance and behavior of endodontically treated maxillary first premolars with substantial loss of tooth structure.
Materials And Methods: Twenty-four extracted endodontically treated human maxillary first premolars were divided into three groups (n = 8) based on ferrule height and post number. The groups were as follows: premolars of 2 mm ferrule height that were restored with single posts (control group), premolars of 0.
Gerodontology
January 2025
Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
Objectives: To identify different clusters of health-related behaviours and examine whether these clusters are associated with maintaining 20 or more teeth.
Background: Engaging in risky behaviours impacts tooth loss, particularly among older adults. Maintaining 20 teeth is a challenge for this age group.
Objective: Denture use has been shown to improve nutritional intake and diet quality in people with tooth loss. Despite evidence linking tooth loss and dementia, few studies have examined the association between denture use and cognitive decline. We investigated the relationship between denture use and cognitive decline among Chinese older adults with tooth loss.
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