The DPC offers many benefits for learners, teachers and developers involved in creation of teaching materials in photobiology. Modifications and additions can be made relatively easily. Anonymous peer review of modules, allowing them to be cited as peer reviewed publications, is likely to encourage new submissions.
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| http://dx.doi.org/10.1039/b316118h | DOI Listing |
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Reliability of the Vitiligo Area Scoring Index measurement tool for vitiligo.
JAAD Int
September 2024
Photomedicine and Photobiology Unit, Department of Dermatology, Henry Ford Health, Detroit, Michigan.
Article Synopsis
- A study aimed to evaluate how consistent and accurate trained raters are when using two versions of the Vitiligo Area Scoring Index (T-VASI and F-VASI) to assess the severity of vitiligo in participants.
- Results showed that inter-rater reliability improved for facial assessments, while overall reliability for full-body assessments was consistently good, indicating the method is effective.
- Limitations included a small sample size and the lack of in-person evaluations, but the findings suggest the Vitiligo Area Scoring Index is a reliable tool for assessing vitiligo severity when used by trained individuals.
The Influence of Blue Light Exposure on Reconstructed 3-Dimensional Skin Model: Molecular Changes and Gene Expression Profile.
JID Innov
March 2024
Natura Cosméticos S/A, São Paulo, Brazil.
Recent studies have provided information about digital eye strain and the potential damage that blue light from digital devices can cause to the eyes. In this study, we analyzed the influence of blue light exposure on reconstructed 3-dimensional skin model using RNA sequencing to identify the expression of transcripts and abnormal events. Three-dimensional skin was exposed to visible light spectrum and isolated blue wavelength for 1, 2, and 4 hours to represent acute exposure and 1 hour over 4 sequential days to represent repeated exposure, respectively, in this in vitro model.
View Article and Find Full Text PDFEnzyme Inhibition-Based Assay to Estimate the Contribution of Formulants to the Effect of Commercial Pesticide Formulations.
Int J Mol Sci
January 2023
Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.
Pesticides can affect the health of individual organisms and the function of the entire ecosystem. Therefore, thorough assessment of the risks associated with the use of pesticides is a high-priority task. An enzyme inhibition-based assay is used in this study as a convenient and quick tool to study the effects of pesticides at the molecular level.
View Article and Find Full Text PDFChildren in Tokyo Have a Long Sustained Axial Length from Age 3 Years: The Tokyo Myopia Study.
J Clin Med
July 2022
Department of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
Background: myopia prevalence is high among Japanese schoolchildren, but the underlying causes are unclear. Objective: To examine the distributions of ocular biometry and refraction and their associations with lifestyle variables among Japanese schoolchildren. Methods: This cross-sectional school-based study included 2140 children aged 3−14 years in Tokyo, Japan, and evaluated the distributions under non-cycloplegic conditions and the associated environmental factors.
View Article and Find Full Text PDFRecommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults.
PLoS Biol
March 2022
Sleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States of America.
Ocular light exposure has important influences on human health and well-being through modulation of circadian rhythms and sleep, as well as neuroendocrine and cognitive functions. Prevailing patterns of light exposure do not optimally engage these actions for many individuals, but advances in our understanding of the underpinning mechanisms and emerging lighting technologies now present opportunities to adjust lighting to promote optimal physical and mental health and performance. A newly developed, international standard provides a SI-compliant way of quantifying the influence of light on the intrinsically photosensitive, melanopsin-expressing, retinal neurons that mediate these effects.
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