AI Article Synopsis

  • A patient experienced severe eye damage due to long-term use of hydrogen peroxide as an eye wash, leading to significant corneal and conjunctival toxicity.
  • The study involved detailed examinations and a surgical procedure, including penetrating keratoplasty and amniotic membrane transplantation, to address the resulting complications.
  • This case underscores the importance of comprehensive medical histories and questioning patients about their eye treatment practices to ensure accurate diagnoses and effective treatment.

Article Abstract

Purpose: To report a patient with severe corneal and conjunctival toxicity from long-term, habitual use of hydrogen peroxide as an eye wash.

Design: Observational case report.

Intervention And Testing: Serial examinations of the cornea, conjunctiva, and ocular adnexa were done. Penetrating keratoplasty with amniotic membrane transplantation was performed.

Main Outcome Measures: Ocular inflammation, pain, and visual acuity outcome.

Results: Bilateral corneal and conjunctival inflammation and scarring mimicking ocular-cicatricial pemphigoid were noted. Formation of a descemetocele after starting treatment with low-dose topical steroids required emergent penetrating keratoplasty with amniotic membrane transplantation.

Conclusions: This is the first reported case of ocular surface toxicity in a patient after deliberate chronic use of high-dose hydrogen peroxide. It highlights the value of obtaining a thorough medical and social history and the importance of direct questioning about the use of any medications or agents on the eyes before making a diagnosis or initiating therapy.

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Source
http://dx.doi.org/10.1016/j.ophtha.2004.01.027DOI Listing

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