Adenoid cystic carcinoma of the parotid metastasizing to liver: case report.

BMC Cancer

Department of Surgical Oncology, M. S. Ramaiah Medical College & Hospital, Bangalore - 560054, India.

Published: July 2004

AI Article Synopsis

  • Adenoid cystic carcinoma is a rare and malignant tumor of the parotid gland that can metastasize years after initial treatment.
  • A 60-year-old female patient had adenoid cystic carcinoma, underwent surgery and radiation, but developed liver metastases three years later, ultimately living for two more years.
  • While liver metastases are unusual for this cancer, patients can survive for several years after metastasis; treatment options include palliative chemotherapy, though surgery to remove metastases is debated.

Article Abstract

Background: Adenoid cystic carcinoma is a rare malignant parotid tumor. Metastasis can occur even a decade or more after initial treatment of the primary.

Case Presentation: We report a 60 year old female patient who presented with adenoid cystic carcinoma of the parotid gland. She underwent a total conservative parotidectomy followed by adjuvant radiotherapy. While on follow up, patient developed multiple liver metastases which manifested three years later. Patient lived for another two years before she died of her disease.

Conclusions: Although distant metastases of adenoid cystic carcinoma develop frequently, isolated metastasis to liver is unusual. Even after manifestation of distant metastasis, patients can be expected to live for a number of years. Palliative chemotherapy can be considered in symptomatic cases while the usefulness of metastasectomy is controversial.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC509249PMC
http://dx.doi.org/10.1186/1471-2407-4-41DOI Listing

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