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Neonatal lupus erythematosus: an acquired autoimmune disease to be taken seriously.
Ann Med
December 2025
Department of Neonatology, Children's Hospital of Soochow University, Suzhou, China.
Aim: This review aims to summarize the epidemiology, pathogenesis, clinical features, management, prognosis and regression of Neonatal lupus erythematosus (NLE) with a view to providing directions for standardized diagnosis, treatment and further research.
Methods: We conducted a comprehensive literature review of NLE. NLE-related peer-reviewed papers were searched through PubMed/Medline were searched up to November 2024.
Diagnostic accuracy of artificial intelligence models in detecting congenital heart disease in the second-trimester fetus through prenatal cardiac screening: a systematic review and meta-analysis.
Front Cardiovasc Med
February 2025
Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Background: Congenital heart disease (CHD) is a major contributor to morbidity and infant mortality and imposes the highest burden on global healthcare costs. Early diagnosis and prompt treatment of CHD contribute to enhanced neonatal outcomes and survival rates; however, there is a shortage of proficient examiners in remote regions. Artificial intelligence (AI)-powered ultrasound provides a potential solution to improve the diagnostic accuracy of fetal CHD screening.
View Article and Find Full Text PDFPregnancy and pulmonary artery hypertension: Management challenges.
Int J Cardiol Congenit Heart Dis
March 2025
Department of Obstetrics, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
Pulmonary hypertension (PH) is a term used to describe a complex heterogenous group of conditions defined by a mean pulmonary arterial pressure of more than 20 mmHg at rest on right-heart catheterization. PH in pregnancy is associated with high rates of maternal morbidity and mortality and poor fetal outcomes. Currently, pregnancy in these women is classified as modified WHO class IV (pregnancy contraindicated).
View Article and Find Full Text PDFThe root of the matter: Linking oral health to chronic diseases prevention.
Int J Cardiol Congenit Heart Dis
March 2025
UCL Eastman Dental Institute, Periodontology Unit, London, UK.
Oral health is increasingly recognized as a vital component of general health, influencing various systemic systems. Periodontal diseases, particularly periodontitis, a chronic inflammatory condition affecting the gums and supporting tissues of teeth, have far-reaching implications beyond the oral cavity. Treating periodontitis not only benefits oral health but also plays a crucial role in reducing the burden of these chronic conditions, improving patient outcomes and lowering healthcare costs.
View Article and Find Full Text PDFThromboprophylaxis and adult congenital heart disease: The latest on indications, risk scoring and therapy.
Int J Cardiol Congenit Heart Dis
March 2025
Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation, London, United Kingdom.
Advances in medical care have significantly extended the lifespan of patients with congenital heart disease (CHD), allowing most to survive into adulthood. However, they continue to face significant cardiovascular morbidity, particularly atrial arrhythmias (AA), heart failure, and thromboembolic (TE) events. TE events in adult CHD patients arise from various factors, including AA, intracardiac repairs, cyanotic CHD, Fontan palliation, pregnancy, and mechanical heart valves (MHV).
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