The major of two solution-state tautomers observed for an etheno product of 2,6-diaminopurine was identified as the tautomer H-1 on the basis of the recognition of the two-bond coupling between the NH proton and C-9a and the three-bond coupling between the NH proton and C-3a. The couplings were distinguished as being over two- or three bonds by determination of the sign of the coupling using two-dimensional heteronuclear NMR, negative in the former case and positive in the latter case. [structure: see text]
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