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The Use of Sodium Chloride Powder Sachets May Not Increase the Risk of Microplastic Emissions in Nasal Irrigation Fluids: A Preliminary Study.
J Rhinol
November 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Background And Objectives: Microplastics, which originate from the breakdown of larger plastic fragments or are intentionally produced for industrial applications, pose significant human and ecological risks through inhalation, ingestion, and dermal contact. Our study examined the release of microplastics during the preparation of homemade saline solutions, specifically when tearing open powder packets and mixing the powder with water.
Methods: We used commercially available polypropylene nasal irrigation bottles from the Korean market and collected six samples of nasal irrigation fluids.
Budesonide nasal irrigation for chronic rhinosinusitis: a meta-analysis of therapeutic outcomes and safety profile.
Rhinology
December 2024
Department of Otorhinolaryngology - Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Background: Corticosteroids are used in managing Chronic Rhinosinusitis (CRS) through several formulations, including oral steroids and nasal sprays. More recently, incorporating concentrated budesonide respules into high-volume saline irrigations has been proposed to enhance the penetration of topical steroids into the paranasal sinuses. We aim to evaluate the safety and efficacy of budesonide nasal irrigation (BNI) in managing CRS.
View Article and Find Full Text PDFTranscriptomic Profiles of the Nasal Mucosa Following Birch Pollen Provocation Differ Between Birch Pollen-Allergic and Non-Allergic Individuals.
Allergy
December 2024
Department of Dermatology, University Hospital St. Poelten, Karl Landsteiner University of Health Sciences, St. Poelten, Austria.
Article Synopsis
- Birch pollen (BP) exposure leads to significant changes in gene expression and cytokine levels in allergic individuals compared to non-allergic individuals, indicating distinct biological responses.
- RNA sequencing identified 160 genes activated in allergic participants, with specific pathways related to inflammation and immune response being enriched in their nasal secretions.
- The findings suggest that BP allergy triggers unique signaling mechanisms in predisposed individuals, providing insights for future research into allergy treatments.
The Effect of Magnesium Sulfate on Extubation Quality Score and Recovery in Larynx Laser Microsurgery: A Prospective, Randomized, Controlled Study.
J Perianesth Nurs
December 2024
Department of Anesthesiology and Reanimation, Faculty of Medicine, Çukurova University, Adana, Turkey. Electronic address:
Purpose: Laryngeal microsurgery is a challenging surgery because of the risk of airway complications. Therefore, extubation is of significant importance. We aimed to investigate the effect of magnesium sulfate on extubation quality, recovery features, and complications.
View Article and Find Full Text PDFClinical Characteristics of Patients With Symptomatic Nasolacrimal Duct Stenosis.
Ophthalmic Plast Reconstr Surg
December 2024
Adnexal Service, Moorfields Eye Hospital, London, United Kingdom.
Purpose: To characterize symptoms and signs for patients with tearing eye(s) and ipsilateral nasolacrimal duct stenosis (NLDS), as defined by delayed fluorescein disappearance test and ocular reflux of saline during gentle irrigation of a patent drainage system.
Methods: Retrospective case-note review of a consistent grading of 4 symptoms and 7 signs, together with estimates of the degree of fluid reflux and nasal fluid passage on gentle saline syringing. Characteristics, including gender differences, were compared for unilateral or bilateral symptoms.
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