Background: Granuloma faciale is an uncommon disease of unknown etiology that is often misdiagnosed clinically and by general pathologists.
Objective: To describe the clinicopathological features of a series of patients with granuloma faciale.
Methods: Eleven patients diagnosed with granuloma faciale between 1990 and 2002 were included in the study.
Results: Granuloma faciale was diagnosed in 11 patients (9 male and 2 female, mean age 53.45 years). All of them presented facial cutaneous lesions and two of them also developed extrafacial lesions. Histologically, in 8 cases the infiltrate was limited to the upper half of the dermis. Two specimens showed fibrinoid necrosis. Concentric fibrosis around small blood vessels was demonstrated in 5 patients.
Conclusion: The presence of abundant fibrosis in 5 of our patients similar to that observed in erythema elevatum diutinum suggests that granuloma faciale and erythema elevatum diutinum may be produced by similar or the same pathogenic mechanism.
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| http://dx.doi.org/10.1016/j.jaad.2003.11.071 | DOI Listing |
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Article Synopsis
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