Burn trauma leads to increased production of reactive oxygen species and compromises the antioxidant systems. The aim of present study was to assess the total antioxidant capacity of plasma (TAC) in burn patients and evaluate its usefulness in clinical practice through analysis of association between TAC and indices of patient prognosis. We investigated TAC in 48 adults and 27 children with severe burn trauma and in 26 healthy controls. TAC was measured on the admission and every week thereafter until discharge or death of patients. The prognosis of the patients was evaluated by the Baux Index and the Abbreviated Burn Severity Index (ABSI). TAC was significantly decreased in both groups with burn trauma as compared with the controls and the decrease was a long lasting event. Significant indirect negative correlation was found between BSAB and TAC values measured in the later phase of injury. In adults an indirect correlation was found between ABSI and the lowest TAC measured on the 7th day or later. Correlations between TAC values and Baux Index were absent both in adults and in children.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Resolvin D2 restores monocyte anisocytosis and mediates a shift toward classical monocytes ex vivo in blood samples from patients after major burns.
FASEB J
January 2025
Department of Surgery, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Circulating monocytes contribute to the defense against pathogens and play a crucial role in maintaining immune homeostasis. While there is substantial evidence regarding the triggers of monocyte activation, our understanding of how monocyte function is restored toward homeostasis after activation remains limited. Here, we assessed the changes in monocyte anisocytosis upon activation in blood, measured by monocyte distribution width (MDW), a biomarker for sepsis.
View Article and Find Full Text PDFClassification and treatment approach of chemical burn associated Limbal stem cell deficiency: based on novel global consensus.
Int Ophthalmol
January 2025
Department of Ophthalmology, Ege University Medical Faculty Hospital, Ege University, 35100, Bornova, Izmir, Turkey.
Purpose: To evaluate the severity distribution of chemical burn-induced Limbal stem cell deficiency (LSCD) according to the novel global consensus classification and to compare the treatment approach, before and after the global consensus.
Methods: Medical records of 127 eyes of 109 patients with LSCD were included. LSCD stages were categorized according to the global consensus classification published by "International LSCD Working Group".
Ideal burn resuscitation: a step toward resolving the dilemma in acute flame burn management.
Int J Burns Trauma
December 2024
Burn Care Center, Pakistan Institute of Medical Sciences (G-8/3), Shaheed Zulfiqar Ali Bhutto Medical University Islamabad, Pakistan.
Following severe burns, the predominant concern is significant fluid loss, for which balanced crystalloid solutions are widely recommended as the primary intravenous resuscitation fluids. However, current literature lacks a clear distinction among various buffered crystalloid types that might be most effective in the early resuscitation of burn patients. This retrospective study was conducted to identify the optimal resuscitation fluid for major burns and to assess the clinical outcomes associated with isotonic crystalloid solutions compared to hypotonic crystalloids, specifically in terms of urinary output, acid-base balance, and electrolyte stability.
View Article and Find Full Text PDFChondromyxoid fibroma of distal phalanx of great toe: a rare case report with literature review.
Int J Burns Trauma
December 2024
Department of Orthopaedic Surgery, J.N. Medical College, Faculty of Medicine, A.M.U. Aligarh, UP, India.
Chondromyxoid fibroma (CMF) in the foot is a rare condition. We report a case of CMF in a 7-year-old girl, affecting the distal phalanx of the great toe. Radiographs revealed a lytic lesion involving the entire distal phalanx, with destruction of both the medial and lateral cortices, while the articular surfaces remained intact.
View Article and Find Full Text PDFSurgical treatment of mammalian bites----experience in the management of facial wounds by dog and cat bite in China.
Int J Burns Trauma
December 2024
Department of Plastic Surgery, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine Nanjing, Jiangsu, China.
Mammalian bites to the face challenges not only related to wound healing but also to aesthetic outcomes. This study aims to summarize 7 years of experience in treating mammalian bite wounds and propose a surgical approach for managing these wounds. From July 2016 to August 2023, 185 cases were treated and retrospectively evaluated.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!