Diabetic retinopathy. Control of systemic factors preserves vision.

Postgrad Med

South Jersey Eye Physicians, Moorestown, New Jersey 08057, USA.

Published: July 2004

Diabetic retinopathy, a retinal microangiopathy, is the leading cause of blindness for persons aged 20 to 65 years in the United States. Routine screening and early treatment are cost-effective and have been shown to help preserve sight. Primary care physicians play a key role in treatment of systemic factors that lead to poor outcomes and referral to an ophthalmologist or a retinal specialist for screening and local treatment. This article, the first of two on retinal vascular disease, provides a review of nonproliferative and proliferative diabetic retinopathy. The second article, which will appear in an upcoming issue of POSTGRADUATE MEDICINE, discusses retinal vascular disease in hypertension.

Download full-text PDF

Source
http://dx.doi.org/10.3810/pgm.2004.07.1558DOI Listing

Publication Analysis

Top Keywords

diabetic retinopathy
12
systemic factors
8
retinal vascular
8
vascular disease
8
retinopathy control
4
control systemic
4
factors preserves
4
preserves vision
4
vision diabetic
4
retinal
4

Similar Publications

The impact of pancreas transplantation on diabetic complications: A systematic review.

Transplant Rev (Orlando)

January 2025

Faculty of Biology, Medicine & Health, University of Manchester, UK; Manchester Centre for Transplantation, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, UK.

Background: Pancreas Transplantation (PT) provides optimal treatment for patients with severe complicated Type 1 Diabetes Mellitus (T1DM). Restoration of beta-cell mass allows return to euglycaemia and insulin independence. We aimed to examine its impact on the secondary complications associated with severe T1DM including diabetic eye disease, neuropathy and cardiovascular disease.

View Article and Find Full Text PDF

Clinical Features Evaluation of Myopic Fundus tessellation from OCTA and MfERG.

Photodiagnosis Photodyn Ther

January 2025

Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, Zhejiang, 315000, P.R. China. Electronic address:

Purpose: To evaluate the differences in fundus tessellation among various severities using multifocal visual electrophysiology (MfERG) and optical coherence tomography angiography (OCTA) for clinical grading and treatment.

Methods: This study included 52 patients totaling 87 eyes. The Early Treatment Diabetic Retinopathy Study (ETDRS) grid division method was utilized to assess Grade of fundus tessellation.

View Article and Find Full Text PDF

Clinical Relevance: Although laser refractive surgeries and multifocal intraocular lens implantation are generally avoided in patients with diabetic retinopathy, a substantial proportion of well-glycaemic-controlled type 2 diabetes mellitus patients are considered for these procedures. Pupil dynamics play a significant role in determining postoperative satisfaction in these patients.

Background: To evaluate pupillary dynamics in patients with and without diabetes following uneventful phacoemulsification surgery.

View Article and Find Full Text PDF

Neovascular age-related macular degeneration and diabetic macular edema are leading causes of vision-loss evoked by retinal neovascularization and vascular leakage. The glycoprotein microfibrillar-associated protein 4 (MFAP4) is an integrin αβ ligand present in the extracellular matrix. Single-cell transcriptomics reveal MFAP4 expression in cell-types in close proximity to vascular endothelial cells including choroidal vascular mural cells and retinal astrocytes and Müller cells.

View Article and Find Full Text PDF

Thrombolytic efficacy and safety of recombinant scu-PA in a rabbit retinal vein occlusion model.

Eur J Pharmacol

January 2025

Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital. Electronic address:

Retinal vein occlusion (RVO) has become the second most common retinal vascular disease after diabetic retinopathy. Existing therapeutic approaches, including intravitreal injection of antivascular endothelial growth factors (anti-VEGFs) and/or glucocorticoids and laser therapy, primarily address secondary macular edema and neovascularisation. However, these strategies do not address the underlying cause of the disease and may have harmful side effects.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!