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Ultrafast dynamic contrast-enhanced breast MRI with quantitative perfusion parameters in differentiating breast cancer: a study focusing on triple-negative and HER2 positive breast cancer.
Front Oncol
January 2025
Department of Radiology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Background: In the realm of breast cancer diagnosis and treatment, accurately discerning molecular subtypes is of paramount importance, especially when aiming to avoid invasive tests. The updated guidelines for diagnosing and treating HER2 positive advanced breast cancer, as presented at the 2021 National Breast Cancer Conference and the Annual Meeting of the Chinese Society of Clinical Oncology, highlight the significance of this approach. A new generation of drug-antibody combinations has emerged, expanding the array of treatment options for HER2 positive advanced breast cancer and significantly improving patient survival rates.
View Article and Find Full Text PDFClinical Efficacy of Ultrafast Dynamic Contrast-Enhanced MRI Using Compressed Sensing in Distinguishing Benign and Malignant Soft-Tissue Tumors.
Korean J Radiol
January 2025
Research Scientist, AIRS Medical Inc., Seoul, Republic of Korea.
Objective: To evaluate the clinical efficacy of ultrafast dynamic contrast-enhanced (DCE)-MRI using a compressed sensing (CS) technique for differentiating benign and malignant soft-tissue tumors (STTs) and to evaluate the factors related to the grading of malignant STTs.
Materials And Methods: A total of 165 patients (96 male; mean age, 61 years), comprising 111 with malignant STTs and 54 with benign STTs according to the 2020 WHO classification, underwent DCE-MRI with CS between June 2018 and June 2023. The clinical, qualitative, and quantitative parameters associated with conventional MRI were also obtained.
CMUT for ultrafast passive cavitation detection during ultrasound-induced blood-brain barrier disruption: proof of concept study.
Phys Med Biol
October 2024
Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, SHFJ, Orsay, France.
Cavitation dose monitoring plays a key role in ultrasound drug delivery to the brain. The use of capacitive micromachined ultrasonic transducer (CMUT) technology has a great potential for passive cavitation detection (PCD).Here, a circular (diameter 7 mm) CMUT centered at 5 MHz was designed to be inserted into a therapeutic transducer (1.
View Article and Find Full Text PDFUnveiling the potential of ultrasound in brain imaging: Innovations, challenges, and prospects.
Ultrasonics
January 2025
School of Information Science and Technology, Fudan University, Shanghai 200433, China. Electronic address:
Article Synopsis
- - Ultrasound is a vital medical imaging tool for brain imaging and disease diagnosis, offering benefits like safety and speed over MRI and CT scans, although it struggles with challenges from the skull's acoustic properties.
- - Technological advancements in ultrasound include various imaging methods such as structural imaging, blood flow imaging, functional imaging, and improved image enhancement techniques, all aimed at better assessing brain structure and function.
- - Recent research highlights these ultrasound techniques' potential in clinical applications for brain disease diagnosis and monitoring cerebral blood flow in both animal models and humans.
The utility of ultrafast MRI and conventional DCE-MRI for predicting histologic aggressiveness in patients with breast cancer.
Acta Radiol
October 2024
Department of Radiology, CHA Bundang Medical Center, CHA University, 59 Yatap-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 13496, Republic of Korea.
Background: Prediction of histologic prognostic markers is important for determining management strategy and predicting prognosis.
Purpose: To identify important features of ultrafast and conventional dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) that can predict histopathologic prognostic markers in patients with breast cancer.
Material And Methods: Preoperative MRI scans of 158 consecutive women (mean age = 54.
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