Role of flagellum and motility in pathogenesis of Vibrio vulnificus.

Infect Immun

Department of Parasitology and Institute of Tropical Medicine, BK21 Project for Medical Science, Yonsei University, Seoul 120-752, Korea.

Published: August 2004

To assess the role of the flagellum which was detected by immunoscreening of surface proteins of Vibrio vulnificus, an flgE-deleted mutant was constructed and tested for its pathogenicity. The ability of this nonmotile mutant to adhere to INT-407 cells and its role in biofilm were decreased, as was its lethality to mice.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC470688PMC
http://dx.doi.org/10.1128/IAI.72.8.4905-4910.2004DOI Listing

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