AI Article Synopsis
- The study focused on how molecules move through microchannels made of poly(dimethylsiloxane) using two different fabrication methods: UV-photolithography and synchrotron radiation (SR)-lithography.
- Researchers utilized a fluorescent probe, sulforhodamine B, to assess molecular dispersion within the channels and found that SR-lithography channels performed better.
- Surface conditions observed through scanning electron microscopy indicated that the difference in channel performance was linked to surface roughness, supporting the findings with chromatographic data consistent with previous studies on glass microchannels.
Article Abstract
In the present paper, a study was undertaken of molecular transport in ploy(dimethylsiloxane) microchannels that were fabricated by ultraviolet (UV)-photolithography and synchrotron radiation (SR)-lithography characterized and compared for microchip capillary electrophoresis by evaluating in-channel molecular dispersion. A fluorescent tag, sulforhodamine B was used as the probing molecule. It was found that microchannels made by SR-lithography fabrication were superior to those made by UV-photolithography fabrication in terms of molecular transport performance. A deep insight into surface conditions characterized by scanning electron microscopy suggested it was related to the difference in surface roughness. Chromatographic retention in electropherograms further supported such a conclusion, which depended on the phase ratio of the channel surface. The results revealed for PDMS microchannels in this work were in good agreement with the phenomenon found for glass microchannels in the literature.
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| http://dx.doi.org/10.1039/b315674e | DOI Listing |
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