[Sildenafil citrate for erectile dysfunction in male kidney transplant recipients].

Zhonghua Nan Ke Xue

Renal Disease Research Center, Department of Urinary Surgery, XinQiao Hospital, Third Military Medical University, Chongqing 400037, China.

Published: June 2004

Objective: To evaluate the efficacy and safety of sildenafil citrate in man kidney transplant recipients with erectile dysfunction.

Methods: One hundred and seventy married males, aged 26 approximately 50 years, who had received kidney transplantations at least half a year before and whose serum creatinine was under 133 umol/l, were selected randomly in the study. Their sexual function was investigated according to the International Index of Erectile Function-5 (IIEF-5), and those with erectile dysfunction (ED) were treated with oral sildenafil citrate for 6 months. The efficacy was assessed by IIEF-5.

Results: Fifty-three men with ED received oral sildenafil citrate for 6 months. At the end of the treatment, each index in IIEF-5 increased significantly. There were no interactions between sildenafil and cyclosporine and there was no significant adverse effect of sildenafil on the graft function.

Conclusion: Sildenafil is an effective and safe agent for the treatment of ED in kidney transplant recipients.

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