Objective: To evaluate the efficacy and safety of sildenafil citrate in man kidney transplant recipients with erectile dysfunction.
Methods: One hundred and seventy married males, aged 26 approximately 50 years, who had received kidney transplantations at least half a year before and whose serum creatinine was under 133 umol/l, were selected randomly in the study. Their sexual function was investigated according to the International Index of Erectile Function-5 (IIEF-5), and those with erectile dysfunction (ED) were treated with oral sildenafil citrate for 6 months. The efficacy was assessed by IIEF-5.
Results: Fifty-three men with ED received oral sildenafil citrate for 6 months. At the end of the treatment, each index in IIEF-5 increased significantly. There were no interactions between sildenafil and cyclosporine and there was no significant adverse effect of sildenafil on the graft function.
Conclusion: Sildenafil is an effective and safe agent for the treatment of ED in kidney transplant recipients.
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Clin Kidney J
January 2025
Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia.
Background: The symptoms, comorbidities and treatment burden associated with chronic kidney disease (CKD) can be debilitating and limit life participation in patients with CKD not requiring kidney replacement therapy (KRT). The aim of this study was to identify the characteristics, content and psychometric properties of patient-reported outcome measures (PROMs) used to assess life participation in patients with CKD.
Methods: We searched MEDLINE, Embase, PsycINFO and CINAHL from database inception to February 2023 for all studies that reported life participation in patients with CKD (stages 1-5 not requiring kidney replacement therapy).
Eur Urol Open Sci
January 2025
Department of Urology, Hospital Universitari de Bellvitge, Barcelona, Spain.
The indication for kidney transplantation over a urinary diversion (UD) for patients with severe lower urinary tract dysfunction and end-stage renal disease is a controversial issue. Thanks to advances in robot-assisted kidney transplant (RAKT) programs, the boundaries are being pushed further. We present the first RAKT series reported for patients undergoing simple cystectomy and UD for benign bladder disease.
View Article and Find Full Text PDFKidney Int Rep
January 2025
Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Introduction: Muscles are crucial for daily activities, and kidney transplant recipients (KTRs) often have reduced muscle mass and strength. We aimed to investigate the potential relationship of muscle mass and strength with physical health-related quality of life (HRQoL) in KTRs.
Methods: Data from the TransplantLines Biobank and Cohort Studies were used.
Kidney Int Rep
January 2025
Department of Immunology and Immunogenetics, Centre Hospitalier Universitaire de Limoges, Limoges, France.
Kidney Int Rep
January 2025
Division of Nephrology, Department of Medicine, University of California San Francisco, California, USA.
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