Dipeptide binding in water by a de novo designed guanidiniocarbonylpyrrole receptor.

J Am Chem Soc

Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Wuerzburg, Germany.

Published: July 2004

A new dipeptide receptor 9, which was designed de novo based on theoretical calculations, efficiently binds dipeptides in water with Kass > 104 M-1 by a combination of ion pairing and hydrogen bonds as can be shown by UV-titration and NMR experiments.

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Source
http://dx.doi.org/10.1021/ja048587vDOI Listing

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