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[Late forced emigration without perspectives: Alfred Hauptmann and Adolf Wallenberg].
Nervenarzt
October 2022
Institut für Geschichte, Theorie und Ethik der Medizin, Medizinische Fakultät und Universitätsklinikum, Heinrich-Heine-Universität, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Archival documents and further biographical testimonies reveal that dismissal and expulsion on racist grounds also affected neurologists in leading clinical positions and at an advanced age. Alfred Hauptmann (1881-1948), full professor for neurology and psychiatry in Halle/Saale, member of the Leopoldina and discoverer of phenobarbitone treatment for epilepsy, emigrated first to Switzerland and then to the USA after the anti-Jewish pogroms in November 1938 and a subsequent "protective custody" imposed on him at the age of 58 years. Adolf Wallenberg (1862-1949), a self-made neurologist, described the syndrome later named after him in 1895.
View Article and Find Full Text PDFDictionary Pruning with Visual Word Significance for Medical Image Retrieval.
Neurocomputing (Amst)
February 2016
Dept of Informatics, University of Albany State University of New York, United States; Robotics Institute, Carnegie Mellon University, United States.
Content-based medical image retrieval (CBMIR) is an active research area for disease diagnosis and treatment but it can be problematic given the small visual variations between anatomical structures. We propose a retrieval method based on a bag-of-visual-words (BoVW) to identify discriminative characteristics between different medical images with Pruned Dictionary based on Latent Semantic Topic description. We refer to this as the PD-LST retrieval.
View Article and Find Full Text PDF[Adélaïde Hautval (1906-1988): An exemplary medical personality].
Presse Med
December 2015
Faculté de médecine de Strasbourg, 67000 Strasbourg, France.
Adélaïde Hautval (1906-1988), psychiatrist, was arrested in April 1942 having defended a Jewish family abused by German soldiers. She was imprisoned in Bourges and in several camps in France (Pithiviers, Beaune-la-Rolande, Orléans, Romainville) before being deported as a "Friend of the Jews" at Auschwitz in the convoy of 23 January 1943, said 31,000 convoy with 229 other resistant women, Marie-Claude Vaillant-Couturier, Charlotte Delbo, Danielle Casanova. She refused to participate in the "medical" experience of Nazi doctors Clauberg, Schumann, Wirths and Mengele at Birkenau.
View Article and Find Full Text PDFAntiepileptic drug therapy the story so far.
Seizure
December 2010
Epilepsy Unit, Western Infirmary, Glasgow G11 6NT, Scotland, UK.
The story began on 11th May 1857 when Charles Locock commented in the Lancet on his use of potassium bromide in 15 cases of "hysterical" epilepsy in young women. The next development was the serendipitous discovery of the anticonvulsant properties of phenobarbital by Alfred Hauptmann in 1912. This predated by more than 20 years the screening of potential therapeutic agents against "electrical seizures" in cats by Houston Merritt and Tracy Putnam.
View Article and Find Full Text PDFThe zebrafish orphan nuclear receptor genes nr2e1 and nr2e3 are expressed in developing eye and forebrain.
Gene Expr Patterns
February 2007
School of Life Sciences, Södertörns University College, Department of Biosciences and Nutrition, Karolinska Institutet, Alfred Nobels Allé 3, 14152 Huddinge, Sweden.
Mammalian Nr2e1 (Tailless, Mtll or Tlx) and Nr2e3 (photoreceptor-specific nuclear receptor, Pnr) are highly related orphan nuclear receptors, that are expressed in eye and forebrain-derived structures. In this study, we analyzed the developmental expression patterns of zebrafish nr2e1 and nr2e3. RT-PCR analysis showed that nr2e1 and nr2e3 are both expressed during embryonic and post-embryonic development.
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