Cytotoxic-antineoplastic activity of acetyl derivatives of prenylnaphthohydroquinone.

Farmaco

Instituto de Química, Pontificia Universidad Católica de Valparaíso, Avenida Brazil 2950, Casilla 4059 Valparaíso, Chile.

Published: August 2004

Several acetyl derivatives of prenylnaphthohydroquinone have been synthetized and evaluated for their cytotoxicity against A-549 human lung carcinoma and H-116 human colon carcinoma neoplastic cells. The IC50 values against A-549 are compared with those observed for previously reported unsubstituted derivatives.

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http://dx.doi.org/10.1016/j.farmac.2004.03.005DOI Listing

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