AI Article Synopsis
- The study aimed to examine how reduced plaque volume during percutaneous coronary intervention (PCI) affects blood flow in patients with acute myocardial infarction (AMI).
- Researchers analyzed 60 AMI patients using intravascular ultrasound to measure plaque volume before and after PCI, finding that decreased plaque volume correlated with poor coronary flow outcomes.
- The results showed that while plaque volume decreased in all patients post-PCI, those with inadequate blood flow had a significantly larger reduction in plaque volume, suggesting that this reduction might negatively impact recovery after the procedure.
Article Abstract
Objectives: The aim of this study was to evaluate how decreased plaque volume during percutaneous coronary intervention (PCI) affects coronary flow in patients with acute myocardial infarction (AMI).
Background: Coronary flow after reperfusion therapy is a major determinant of clinical outcomes in patients with AMI. However, little is still known about the changes in coronary flow that appear after PCI in response to the decreased plaque during the procedure.
Methods: The study group comprised 60 patients with AMI who underwent pre- and post-PCI intravascular ultrasound (IVUS). Qualitative and quantitative analyses were performed on all IVUS procedures. External elastic membrane volume (EEMV), lumen volume (LV), and plaque volume (PV) were measured every 1.0 mm to include the lesion and reference segments 3.0 mm proximal and distal to the lesion. The difference between pre- and post-PCI PV was defined as the index of the decrease in plaque volume (DeltaPV). The corrected TIMI frame count (CTFC) was used to evaluate coronary flow after PCI.
Results: Plaque volume was decreased at post-PCI IVUS in all 60 patients. Inadequate reflow (CTFC >40) was observed in 13 patients (21.7%). The decrease in PV was significantly larger in patients with inadequate reflow than in those with reflow (49.4 +/- 18.9 vs. 31.7 +/- 15.5 mm(3), p = 0.0010). Also, DeltaPV was significantly correlated with CTFC after PCI (r = 0.415, p = 0.0012).
Conclusions: The decrease in PV during PCI has a negative impact on coronary flow after PCI in patients with AMI. Embolization induced by PCI may occur in all patients with AMI.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jacc.2004.04.036 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Anatomy versus Shunt Fraction: Hemodynamic Consequences in Atrial Septal Defects and Partial Anomalous Pulmonary Venous Connection - A comprehensive CMR study.
Eur Heart J Cardiovasc Imaging
January 2025
Department of Radiology, UZ Leuven, Leuven, Belgium.
Aims: Atrial septal defect (ASD) and partial abnormal pulmonary venous connection (PAPVC) are noncyanotic congenital heart defects (CHD) that produce a left-to-right shunt. This single-center retrospective study aimed to assess the hemodynamic impact of isolated ASD, isolated PAPVC, and ASD-associated PAPVC using cardiovascular magnetic resonance (CMR).
Methods And Results: From our CMR registry (2002-2024), 110 patients were included: isolated ASD (n=64), isolated PAPVC (n=18), ASD-associated PAPVC (n=28, mostly sinus venosus septal defects).
Ventricular fibrillation caused by massive right coronary air embolism: a case report.
Egypt Heart J
January 2025
Department of Cardiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.
Background: Coronary air embolism is a rare but severe complication of coronary interventions.
Case Presentation: We present a case of a massive air embolism in the right coronary artery during percutaneous coronary intervention, resulting in ventricular fibrillation. The patient was successfully resuscitated with electric defibrillation, leading to full recovery and TIMI 3 coronary flow.
Adrenal gland size in fetuses with congenital heart disease.
J Perinat Med
January 2025
Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany.
Objectives: The aim of this study was to compare the adrenal gland size of fetuses with congenital heart diseases (CHD) and normal fetuses.
Methods: In this cross-sectional prospective study we measured the fetal adrenal gland size (total width, cortex width, medulla width, adrenal gland ratio of total width divided by medulla width) in 62 fetuses with CHD and 62 gestational-age-matched controls between 20 + 0 and 39 + 3 weeks of gestation. First, we clustered three CHD subgroups: CHD group_1 with a normal outflow tract (n=7), CHD group_2 with an altered outflow tract and anterograde flow in the ascending aorta (n=39) and CHD group_3 with an altered outflow tract and retrograde flow in the ascending aorta (n=16).
Purpose: The aim of the current study was to evaluate changes in choroidal circulation hemodynamics after periocular skin warming at 40°C using laser speckle flowgraphy (LSFG).
Methods: Twenty-four right eyes of 24 healthy participants were included. Changes in choroidal circulation hemodynamics were determined using LSFG to evaluate the mean blur rate (MBR) of the macula, which represents choroidal blood flow velocity.
Acute Coronary Syndrome in a 40-Year-Old Male With Coronary Ectasia: A Case Report.
Cureus
December 2024
Zulekha Hospital, Intensive Care Unit, Sharjah, ARE.
Coronary artery ectasia (CAE) is a relatively uncommon condition that is often identified incidentally during coronary angiography. It can lead to altered hemodynamics and an increased risk of thrombotic events. This case report outlines the clinical progression of a 40-year-old male diagnosed with acute coronary syndrome (ACS).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!