Novel 4"-alkoxy avermectin derivatives were synthesized via rhodium carbenoid mediated O-H insertion reaction and tested for antiparasite activity against Artemia salina and Caenorhabditis elegans.
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School of Chemistry, Indian Institute of Science Education and Research, Thiruvananthapuram, Kerala 695551, India.
This study demonstrates the direct conversion of vinylogous esters into selectively protected 6-acyl resorcinols (4-alkoxy/aryloxy-2-hydroxy arylketones) in a regiospecific manner. Resorcinyl ketones are first-time synthesized, diverging from their traditional roots, originating from non-benzenoid pool materials. Converting cyclohexenones into phenol- or resorcinol-based arylketones remains challenging due to the stability and reactivity issues of intermediate products.
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Unité Matériaux et Transformations (UMET), UMR 8207-CNRS, University Lille, CNRS, INRAE, Centrale Lille, F-59000 Lille, France.
Liquid crystals with high dielectric anisotropy, low operational thresholds, and significant birefringence (Δ) represent a key focus in soft matter research. This work introduces a novel series of hydrogen-bonded liquid crystals (HBLCs) derived from 4-n-alkoxybenzoic, 4-alkoxy-3-fluorobenzoic derivatives (nOBAF), 4-alkoxy-2,3-fluorobenzoic derivatives (nOBAFF), and 2-fluoro-4-nitrobenzoic acid. The HBLCs were characterized using Fourier transform infrared spectroscopy, and their thermal behavior was evaluated via differential scanning calorimetry.
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Department of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah, Saudi Arabia.
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Department of Oral Biochemistry, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, 61186, Republic of Korea. Electronic address:
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