The major role for chromoendoscopy in the esophagus is the identification of premalignant or early cancerous lesions. In combination with high-resolution or magnification endoscopes, chromoendoscopy can potentially increase the diagnostic yield of clinically relevant lesions. Preliminary data have indicated a good correlation of findings using this technique to histopathologic readings. The ultimate goal of chromoendoscopy in combination with high resolution/magnification endoscopy is the determination of histology without obtaining tissue samples. In this article we review the different stains, the technical aspects, and current data in esophageal chromoendoscopy. We summarize possible clinical applications of these techniques and future directions of their use in esophageal diseases.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.giec.2004.03.003 | DOI Listing |
Indian J Otolaryngol Head Neck Surg
December 2024
Department of Gastroenterology, Christian Medical College, Vellore, Tamil Nadu 632004 India.
Objective: To study the prevalence of synchronous oesophageal cancer in patients with head and neck cancers using Narrow Band Imaging and Lugol's chromoendoscopy.
Materials And Methods: Study design: Prospective cross sectional diagnostic study. Method: 63 recruited patients with head and neck cancers, underwent haematologic evaluation, histological confirmation, imaging which included contrast enhanced computerised tomography(CECT) of the Neck and when indicated an additional Magnetic Resonance Imaging(MRI) scan followed by UGI endoscopy using white light followed by Narrow Band Imaging(NBI) and Lugol's chromoendoscopy(LCE).
Gastroenterol Clin North Am
December 2024
Division of Gastroenterology and Hepatology, University of Virginia, Box 800708, Charlottesville, VA 22908, USA. Electronic address:
Recent advancements in endoscopy, including high-definition imaging, virtual chromoendoscopy, and optical magnification, have enhanced our ability to visualize and diagnose certain esophageal diseases. Innovative endoscopic tools and procedures have been developed to broaden the scope of therapeutic options for treating patients with various esophageal conditions. This comprehensive review aims to elucidate the esophageal anatomy and major disorders from an endoscopist's perspective and explore recent advances in endoscopic treatment.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
August 2024
State Key Laboratory of Molecular Oncology, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Genetics, Peking University Cancer Hospital & Institute, Beijing, China. Electronic address:
Background & Aims: The aim of this study was to investigate the persistence of Lugol-unstained lesions (LULs) in the esophagus detected by chromoendoscopy and explore their association with progression to malignancy.
Methods: We enrolled 647 participants from a population-based screening trial who had biopsied LULs at the baseline chromoendoscopy and underwent a chromoendoscopy re-examination after a median of 4.39 years.
Am J Gastroenterol
December 2024
Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA.
United European Gastroenterol J
October 2024
Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!