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Navigating DR-TB Treatment care: a qualitative exploration of barriers and facilitators to retention in care among people with history of early disengagement from drug-resistant tuberculosis treatment in Johannesburg, South Africa.
BMC Health Serv Res
January 2025
HIV and Other Infectious Diseases Research Unit (HIDRU), South African Medical Research Council: CAPRISA-MRC HIV-TB Pathogenesis and Treatment Research Unit, Free State, South Africa.
Background: Despite advances in drug-resistant tuberculosis (DR-TB) diagnosis, treatment, and service delivery, individuals with DR-TB often face significant socioeconomic and psychosocial challenges due to limited resources. These challenges can hinder retention in care, undermining the progress made in DR-TB management. As a consequence, advances in DR-TB diagnostics and treatment have not resulted in DR-TB programs meeting the 75% treatment success targets set by the World Health Organization (WHO).
View Article and Find Full Text PDFSyncopal reactions in blood donors: Pathophysiology, clinical course, and features.
Asian J Transfus Sci
September 2022
Department of Physiology, Mahatma Gandhi Medical College, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, India.
Vasovagal syncope (VVS) in donors is a transient loss of consciousness due to short-term global cerebral hypoperfusion, which has a rapid onset and has complete spontaneous recovery. VVS may be triggered by pain, fear, anxiety, or emotional upset and loss of blood perse. It is an exaggeration of an adaptive response meant to assist in reducing the amount of bleeding/loss of blood.
View Article and Find Full Text PDFComparative Evaluation of Different Pain-alleviating Methods on Child's Dental Anxiety and Pain Perception during Local Anesthesia Administration: A Clinical Study.
Int J Clin Pediatr Dent
November 2024
Private Practitioner, Gujarat, India.
Background: When it comes to reducing children's fear, anxiety, and discomfort during dental procedures, substantial local anesthetic delivery promotes adequate intervention. In the dental operatory, local anesthetic injections are the most anticipated or feared stimuli. The application of topical anesthetics, cryotherapy, and transcutaneous electrical nerve stimulation (TENS) to the oral mucosa prior to local anesthetic injections can alter pain perception in children.
View Article and Find Full Text PDFSentiment analysis of tweets employing convolutional neural network optimized by enhanced gorilla troops optimization algorithm.
Sci Rep
January 2025
University of Ghana, P.O. Box 134, Legon-Accra, Ghana.
Sentiment analysis has become a difficult and important task in the current world. Because of several features of data, including abbreviations, length of tweet, and spelling error, there should be some other non-conventional methods to achieve the accurate results and overcome the current issue. In other words, because of those issues, conventional approaches cannot perform well and accomplish results with high efficiency.
View Article and Find Full Text PDFInvolvement of the parabrachial nucleus in emergence from general anesthesia.
Front Neurosci
December 2024
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
The parabrachial nucleus (PBN), located in the dorsolateral pons, is involved in many important biological functions, such as sensory signaling, feeding, defensive behaviors, fear, anxiety, and sleep-wake cycles. General anesthesia shares the classical feature of reversible loss of consciousness with natural sleep, and accumulating evidence has indicated that general anesthesia and sleep-wake behaviors share some common underlying neural mechanism. In recent years, emerging studies have investigated the involvement of PBN in emergence from general anesthesia, but divergence exists in terms of different types of general anesthetics or different durations of treatment with the same group of general anesthetics.
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